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Novel Pathogenic C5 Gene Variants in a Patient with Neisseria Meningitis and Diffuse Cutaneous HSV-1 Infection

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Fig. 1

Data Availability

Not applicable as this is a case report without a data repository. All PHI was protected with HIPAA-regulated guidelines, and author communication was completed in HIPAA-secure communication avenues.

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Funding

No funding was obtained for this study.

Author information

Authors and Affiliations

  1. Department of Allergy and Immunology, Walter Reed National Military Medical Center, 4944 North Palmer Road, Bethesda, MD, 20814, USA

    W. Grant Day & Luke Pittman

  2. Department of Gastroenterology, San Antonio Military Medical Center, San Antonio, TX, USA

    Christian Horn

  3. Department of Genetics, Madigan Army Medical Center, Tacoma, WA, USA

    Jacob S. Hogue

  4. Department of Gastroenterology, Walter Reed National Military Medical Center, Bethesda, MD, USA

    Jared Magee

  5. Allergy Partners of Northern Virginia, Chantilly, VA, USA

    Shahrooz Shayegan

Authors
  1. W. Grant Day
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  2. Christian Horn
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  3. Jacob S. Hogue
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  4. Jared Magee
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  5. Shahrooz Shayegan
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  6. Luke Pittman
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Contributions

Dr. W. GD: Primary author, editing, completed literature review, coordination.

Dr. Luke Pittman: Physician who cared for case patient while in the hospital and follow-up with him afterwards. Assisted with writing, edits.

Dr. Christian Horn: Helped write, edit, proofread article, senior resident of medicine team taking care of case patient while he was in the hospital.

Dr. Jacob Hogue: Geneticist who obtained genetic testing for case patient and reported the specific mutations. Wrote and edited portions of article regarding the patient’s mutations.

Dr. Jared Magee: Helped write, edit, and proofread article.

Dr. Shahrooz Shayegan: Allergist in consultation regarding case patient; followed-up with patient, recommended specific testing for immunodeficiency, helped write, edit, proofread article.

Corresponding author

Correspondence to W. Grant Day.

Ethics declarations

Ethics Approval/Consent to Participate

The patient consented to participate in this report to include laboratory and genetic testing.

Conflict of Interest

All the authors involved in the project declare there are no conflict of interests.

Competing Interests

None of the authors involved in the production of this article have any competing interests to report.

Disclaimer

The views expressed in this article are those of the author(s) and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government.

Copyright Statement

Authors are US military service members. This work was prepared as part of their official duties. Title 17 U.S.C. 105 provides that “Copyright protection under this title is not available for any work of the United States Government.” Title 17 U.S.C. 101 defines United States Government work as a work prepared by a military service member as part of that person’s official duties.

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Day, W.G., Horn, C., Hogue, J.S. et al. Novel Pathogenic C5 Gene Variants in a Patient with Neisseria Meningitis and Diffuse Cutaneous HSV-1 Infection. J Clin Immunol 44, 52 (2024). https://doi.org/10.1007/s10875-024-01651-7

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  • DOI: https://doi.org/10.1007/s10875-024-01651-7

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