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Severe Disseminated Mycobacterium kansasii Infection due to Autoantibodies Against IFN-ɣ

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Fig. 1

Data Availability

All data generated or analyzed during this study are included in this published article and its supplementary information files.

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Not applicable.

References

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Acknowledgements

We are grateful to the patient’s family and thank them for trusting our laboratory and participating in the study. Thanks to Dr. Zhengbang Dong and Dr. Fei Wang for preparing the patient’s clinical materials.

Funding

This manuscript was supported by grants from the Chinese Academy of Medical Science Innovation Fund for Medical Science (2017-I2M-B&R-14, 2016-I2M-1–005), Jiangsu Provincial Science and Technology Project (BE2018619), National Science and Technology Major Project (2018ZX10101-001), Graduate Innovation Foundation of Peking Union Medical College (2018–1002-02–13), and the National Natural Science Foundation of China (grant 81972950).

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Authors and Affiliations

  1. Institute of Dermatology & Hospital of Skin Diseases, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu, China

    Chun Pan, Wenyue Zhang & Hongsheng Wang

  2. Department of Dermatology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China

    Zhengbang Dong & Fei Wang

Authors
  1. Chun Pan
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  2. Zhengbang Dong
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  3. Wenyue Zhang
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  4. Fei Wang
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  5. Hongsheng Wang
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Contributions

CP and WZ performed the experiments. HW and FW designed and guided this research study. CP wrote the manuscript. ZD and WZ assisted in material preparation, in data collection, and in writing and revising the manuscript. All authors provided intellectual input for the study and approved the final manuscript.

Corresponding author

Correspondence to Hongsheng Wang.

Ethics declarations

Ethics Approval and Consent to Participate

The study was approved by the Ethics Committee of the Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College (2018-KY-019), and was conducted according to the Declaration of Helsinki principles. Written informed consent was obtained from the patient for clinical and genetic investigation.

Consent for Publication

Written informed consent for publication of clinical details and/or clinical images was obtained from the patient. Copies of the consent forms are available for review.

Competing Interests

The authors declare no competing interests.

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Supplementary Information

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Supplementary file1 (DOC 22007 KB)

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Cite this article

Pan, C., Dong, Z., Zhang, W. et al. Severe Disseminated Mycobacterium kansasii Infection due to Autoantibodies Against IFN-ɣ. J Clin Immunol 43, 76–79 (2023). https://doi.org/10.1007/s10875-022-01362-x

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  • DOI: https://doi.org/10.1007/s10875-022-01362-x

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