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B-Cell Immune Reconstitution with Mixed Chimerism After Hematopoietic Cell Transplantation in a Patient with Severe Combined Immunodeficiency

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The availability of the data is subject to prior request to the corresponding author.


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We thank to the patient and her parents for providing the samples. We thank all staff who were involved in the patient’s treatment in the Department of Pediatrics, Tokyo Medical and Dental University Hospital, and the Department of Pediatrics, Kitasato University Hospital.

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Authors and Affiliations



SM, KE, and HK designed the research, wrote the manuscript, treated the patient, collected clinical data, and designed the figures. EW performed and analyzed the flow cytometry and designed the figures and the tables. TM revised the manuscript. All authors read and agreed to the published version of the manuscript.

Corresponding author

Correspondence to Hirokazu Kanegane.

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The studies involving human participants were reviewed and approved by the Institutional Review Boards at Tokyo Medical and Dental University.

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The guardians of the patient provided written informed consent for research use of their data and publication.

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The authors declare no competing interests.

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Miyamoto, S., Ebato, T., Watanabe, E. et al. B-Cell Immune Reconstitution with Mixed Chimerism After Hematopoietic Cell Transplantation in a Patient with Severe Combined Immunodeficiency. J Clin Immunol (2022).

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