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Myelodysplastic Syndrome in a Patient with IPEX Syndrome

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Acknowledgements

We thank Dr. Kenichi Yoshida and Dr. Seishi Ogawa for performing whole exosome sequencing and Enago (https://www.enago.com/) for editing a draft of this manuscript.

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Author notes

  1. Daisuke Toyama and Akihiro Hoshino contributed equally to this work.

Authors and Affiliations

  1. Department of Pediatrics, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan

    Daisuke Toyama & Shohei Yamamoto

  2. Department of Pediatrics, Tokai University School of Medicine, Isehara, Kanagawa, Japan

    Daisuke Toyama & Shohei Yamamoto

  3. Department of Pediatrics and Developmental Biology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

    Akihiro Hoshino, Kento Inoue & Takahiro Kamiya

  4. Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

    Hirokazu Kanegane

Authors
  1. Daisuke Toyama
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  2. Akihiro Hoshino
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  3. Kento Inoue
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  4. Takahiro Kamiya
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  5. Hirokazu Kanegane
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  6. Shohei Yamamoto
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Contributions

D.T. and A.H. wrote the manuscript. D.T., A.H., K.I., T.K., H.K., and S.Y. treated the patient. H.K. and S.Y. critically reviewed the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Shohei Yamamoto.

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The authors declare no competing interests.

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Supplementary Information

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Supplementary file2 (XLSX 25 KB)

10875_2021_1092_MOESM3_ESM.pptx

Supplementary file3 (PPTX 67 KB) Supplementary Fig. S1 Identification of autoantibodies. Heat map of proteome microarrays displaying serum IgG reactivities to KLF1, ERCC4, G6PD, and CD34 in the present patient, 3 patients with IPEX syndrome without MDS, and 2 healthy subjects [9].

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Toyama, D., Hoshino, A., Inoue, K. et al. Myelodysplastic Syndrome in a Patient with IPEX Syndrome . J Clin Immunol 41, 1683–1685 (2021). https://doi.org/10.1007/s10875-021-01092-6

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  • DOI: https://doi.org/10.1007/s10875-021-01092-6

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