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Chronic Disseminated Gonococcal Infection in a Japanese Man with Novel C5 Gene Mutation

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Fig. 1

Data Availability

The data from this study are available from the corresponding author, KO, upon reasonable request.

References

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Acknowledgments

We thank Katsuki Ohtani (Department of Clinical Nutrition, Rakuno Gakuen University, Japan), Yasuo Fukumori (Department of Molecular Genetics, Wakayama Medical University, Japan), and Nobutaka Wakamiya (Department of Medicine and Physiology, Rakuno Gakuen University, Japan) for the protein and genetic analysis of C5. We would like to thank Editage (www.editage.com) for English language editing.

Funding

This research was supported by the Japanese Association for Complement Research which is funded by Alexion GK and CSL Behring K. K. as a company sponsored research.

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Authors and Affiliations

  1. University of Tokyo Hospital, Bunkyo-ku, Japan

    Kazuhiko Ikeuchi, Koh Okamoto, Shu Okugawa & Kyoji Moriya

  2. IMSUT Hospital of The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

    Kazuhiko Ikeuchi

  3. Department of Infectious Diseases, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Koh Okamoto

  4. Department of Molecular Genetics, Wakayama Medical University, Wakayama, Japan

    Norimitsu Inoue

Authors
  1. Kazuhiko Ikeuchi
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  2. Koh Okamoto
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  3. Norimitsu Inoue
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  4. Shu Okugawa
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  5. Kyoji Moriya
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Contributions

KI and KO conceived the study. KI, KO, SO, and KM were responsible for the clinical management of the patient. NI analyzed levels of complement components and sequenced the C5 gene. All authors revised the drafts and approved the final manuscript.

Corresponding author

Correspondence to Koh Okamoto.

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Conflict of Interest

The authors declare no conflict of interest.

Ethics Approval

This study was approved by the ethics committee of the University of Tokyo Hospital, approval number 2018045G.

Consent to Participate

Written informed consent was obtained from the patient.

Consent for Publication

Written informed consent was obtained from the patient.

Code Availability

Not applicable.

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Ikeuchi, K., Okamoto, K., Inoue, N. et al. Chronic Disseminated Gonococcal Infection in a Japanese Man with Novel C5 Gene Mutation. J Clin Immunol 41, 691–693 (2021). https://doi.org/10.1007/s10875-020-00959-4

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  • DOI: https://doi.org/10.1007/s10875-020-00959-4

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