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Revisiting Fatal Granulomatous Disease of Childhood Through an Autopsy: Still Lethal in the Developing World!

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Fig. 1

Abbreviations

CGD:

chronic granulomatous disease

NADPH:

nicotinamide adenine dinucleotide phosphate

MRSA:

methicillin-resistant Staphylococcus aureus

CECT:

contrast-enhanced computerized tomography

NBT:

nitro blue tetrazolium

DHR:

dihydrorhodamine

References

  1. Bridges RA, Berendes H, Good RA. A fatal granulomatous disease of childhood; the clinical, pathological, and laboratory features of a new syndrome. AMA J Dis Child. 1959;97(4):387–408.

    Article  CAS  PubMed  Google Scholar 

  2. Gupta K, Rawat A, Agrawal P, Jindal A, Nada R, Saikia B, et al. Infectious and non-infectious complications in primary immunodeficiency disorders: an autopsy study from North India. J Clin Pathol. 2018;71(5):425–35.

    Article  CAS  PubMed  Google Scholar 

  3. Marciano BE, Spalding C, Fitzgerald A, Mann D, Brown T, Osgood S, et al. Common severe infections in chronic granulomatous disease. Clin Infect Dis. 2015;60(8):1176–83.

    Article  CAS  PubMed  Google Scholar 

  4. Rawat A, Vignesh P, Sharma A, Shandilya JK, Sharma M, Suri D, et al. Infection profile in chronic granulomatous disease: a 23-year experience from a tertiary care center in North India. J Clin Immunol. 2017;37(3):319–28.

    Article  PubMed  Google Scholar 

  5. Lublin M, Bartlett DL, Danforth DN, Kauffman H, Gallin JI, Malech HL, et al. Hepatic abscess in patients with chronic granulomatous disease. Ann Surg. 2002;235(3):383–91.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Marciano BE, Allen ES, Conry-Cantilena C, Kristosturyan E, Klein HG, Fleisher TA, et al. Granulocyte transfusions in patients with chronic granulomatous disease and refractory infections: the NIH experience. J Allergy Clin Immunol. 2017;140(2):622–5.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Noordhoek GT, Kolk AH, Bjune G, Catty D, Dale JW, Fine PE, et al. Sensitivity and specificity of PCR for detection of Mycobacterium tuberculosis: a blind comparison study among seven laboratories. J Clin Microbiol. 1994;32(2):277–84.

    CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgments

The authors thankfully acknowledge Prof. Surjit Singh, Prof. Anju Gupta, and Dr. Vignesh Pandiarajan for helping in patient care.

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Authors and Affiliations

  1. Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India

    Rakesh Kumar Pilania, Ashwini Prithvi & Amit Rawat

  2. Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India

    Kaniyappan Nambiyar & Kirti Gupta

Authors
  1. Rakesh Kumar Pilania
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  2. Ashwini Prithvi
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  3. Kaniyappan Nambiyar
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  4. Kirti Gupta
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  5. Amit Rawat
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Correspondence to Amit Rawat.

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Pilania, R.K., Prithvi, A., Nambiyar, K. et al. Revisiting Fatal Granulomatous Disease of Childhood Through an Autopsy: Still Lethal in the Developing World!. J Clin Immunol 39, 241–244 (2019). https://doi.org/10.1007/s10875-019-00616-5

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  • DOI: https://doi.org/10.1007/s10875-019-00616-5

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