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Table II PK parameters by age group (PPK population)

From: Efficacy and Safety of Hizentra®, a New 20% Immunoglobulin Preparation for Subcutaneous Administration, in Pediatric Patients with Primary Immunodeficiency

Parameter Children Adolescents Adults
2–11 years 12–15 years 16–64 years
N = 9 N = 3 N = 11
C max (g/L), mean (SD) 8.09 (1.492) 8.60 (1.443) 8.31 (1.096)
T max (day), median (range) 2.06 (0.94–6.92) 1.98 (1.93–2.94) 2.07 (0.95–3.98)
AUC (day × g/L), mean (SD) 52.30 (9.987) 54.91 (11.548) 54.52 (8.672)
  1. PPK per-protocol pharmacokinetic, N number of patients in age group, C max maximum concentration, T max time point of maximum concentration, AUC area under the concentration–time curve until last measured concentration, SD standard deviation