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Synthesis and Crystal Structures of 4-Chloro-N′-(4-hydroxy-3-nitrobenzylidene)benzohydrazide monohydrate and 4-Chloro-N′-(4-hydroxy-3-methoxybenzylidene)benzohydrazide monohydrate

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Abstract

Two new hydrazone compounds, 4-chloro-N′-(4-hydroxy-3-nitrobenzylidene)benzohydrazide monohydrate (1) and 4-chloro-N′-(4-hydroxy-3-methoxybenzylidene)benzohydrazide monohydrate (2), were synthesized and characterized by physico-chemical methods and single crystal X-ray diffraction. Compound 1 crystallizes in the monoclinic space group P21/c with unit cell parameters a = 23.257(3) Å, b = 4.829(1) Å, c = 12.763(2) Å, β = 96.017(2)°, V = 1425.5(5) Å3, Z = 4, R 1 = 0.0525, and wR 2 = 0.1120. Compound 2 crystallizes in the monoclinic space group P21/c with unit cell parameters a = 8.103(3) Å, b = 21.321(3) Å, c = 10.594(3) Å, β = 120.281(2)°, V = 1580.5(8) Å3, Z = 4, R 1 = 0.0480, and wR 2 = 0.1078. Both compounds contains a hydrazone molecule and a water molecule. The crystals of the compounds are stabilized by N–H···O, O–H···O, and O–H···N hydrogen bonds.

Graphical Abstract

Two new hydrazone compounds have been synthesized and characterized by physico-chemical methods and single crystal X-ray diffraction.

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Acknowledgments

We acknowledge the Chongqing Three Gorges University for funding this study.

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Authors and Affiliations

  1. School of Chemistry & Environmental Engineering, Chongqing Three Gorges University, Chongqing, 404000, People’s Republic of China

    Yan Lei, Ting-Zhen Li, Chuan Fu, Xiao-Lin Guan & Yao Tan

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  1. Yan Lei
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  2. Ting-Zhen Li
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  3. Chuan Fu
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  4. Xiao-Lin Guan
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Correspondence to Yan Lei.

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Lei, Y., Li, TZ., Fu, C. et al. Synthesis and Crystal Structures of 4-Chloro-N′-(4-hydroxy-3-nitrobenzylidene)benzohydrazide monohydrate and 4-Chloro-N′-(4-hydroxy-3-methoxybenzylidene)benzohydrazide monohydrate. J Chem Crystallogr 41, 1707–1711 (2011). https://doi.org/10.1007/s10870-011-0161-0

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