Abstract
A series of new heterocyclic compounds bearing 1,2,3-triazole moiety were synthesized using 4-acetyl-2-phenyl-1,2,3-triazole 1 as the starting material. The target compounds were prepared and the structures were characterized by IR, 1H NMR, MS and elemental analysis. Meanwhile, the crystal structures of the synthesized compounds were also furthered confirmed by X-ray diffraction analysis. Compound 3b crystallized in the monoclinic P2(1)/c space group with unit cell parameters a = 10.6974(17) Å, b = 20.356(3) Å, c = 7.8049(12) Å, α = 90°, β = 102.840(3)°, γ = 90º, V = 1657.1(5) Å3, Z = 4, T = 293(2) K. Compound 7c crystallized in the Triclinic P-1 space group with unit cell parameters a = 7.364(2) Å, b = 7.366(2) Å, c = 26.089(8)Å, α = 87.114(7)°, β = 87.040(7) (3)°, γ = 82.337(7)°, V = 1399.2(7) Å3, Z = 2, T = 293(2) K. Compound 10c crystallized in the Triclinic P-1 space group with unit cell parameters a = 9.8152(10) Å, b = 10.0806(13) Å, c = 11.1267(14) Å, α = 100.344(3)°, β = 111.975(3)°, γ = 107.852(3)°, V = 916.18(19) Å3, Z = 2, T = 293(2) K.
Graphical Abstract
New heterocyclic compounds bearing 1,2,3-triazole moiety were synthesized, which may have potential biological and medical applications.
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This work was supported by the National Natural Science Foundation of China (Nos. 20562011, 20662009).
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Dong, ZQ., Liu, FM. & Zeng, YM. Synthesis and Crystal Structure of New Heterocyclic Compounds Containing 1,2,3-Triazole Moiety. J Chem Crystallogr 41, 1158–1164 (2011). https://doi.org/10.1007/s10870-011-0063-1
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DOI: https://doi.org/10.1007/s10870-011-0063-1