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Structure of a β-Amino Dicarbonyl Compound: 2-[(4-Chloro-Phenyl)-Pyrrolidin-1-yl-Methyl]-Malonic Acid Diethyl Ester

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Abstract

The titled new functionalized ligand 2-[(4-chloro-phenyl)-pyrrolidin-1-yl-methyl]-malonic acid diethyl ester (4) is prepared in good yield through condensation of pyrazole and 3,5-dimethyl-pyrazole, respectively, with 2-arylidene-malonic acid diethyl esters (3). The structures of (4) is determined by spectral (IR, 1H NMR), elemental analyses and X-ray diffraction data. The structure of (4) was solved in triclinic, space group P-1, with a = 5.6858(2), b = 10.0716(4), c = 16.2885(7) Å, α = 94.338(3, β = 91.453(4), γ = 97.750(3)°, V = 921.00(6) Å3, Z = 2.

Graphical Abstract

[Structures of two β-amino dicarbonyl compounds: 2-[(4-chloro-phenyl)-pyrrolidin-1-yl-methyl]-malonic acid diethyl ester and 2-[(4-chloro-phenyl)-(3,5-dimethyl-pyrazol-1-yl)-methyl]-malonic acid diethyl ester I. Meskini, L. Toupet, M. Daoudi, A. Kerbal, T Ben Hadda The structure of (4) is determined by spectral (IR, 1H NMR), elemental analyses and X-ray diffraction data. It is similar to compound (5).

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Scheme 1
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Acknowledgements

This work was supported by the Centre National de Recherche Scientifique, University of Rennes 1 (France) and University of Mohammed 1 of Oujda (Morocco).

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Authors and Affiliations

  1. Laboratoire de Chimie Organique, Université Sidi Mohammed Ben Abdellah, Fès, Morocco

    Ihssan Meskini, Maria Daoudi & Abdelali Kerbal

  2. Institut de Physique-IPR-UMR CNRS 6251, Université de Rennes 1, Rennes, France

    Loic Toupet

  3. Laboratoire Chimie des Matériaux, FSO, Université Mohammed 1, Oujda, Morocco

    Taibi Ben Hadda

Authors
  1. Ihssan Meskini
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  2. Loic Toupet
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  3. Maria Daoudi
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  4. Abdelali Kerbal
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  5. Taibi Ben Hadda
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Correspondence to Taibi Ben Hadda.

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Meskini, I., Toupet, L., Daoudi, M. et al. Structure of a β-Amino Dicarbonyl Compound: 2-[(4-Chloro-Phenyl)-Pyrrolidin-1-yl-Methyl]-Malonic Acid Diethyl Ester. J Chem Crystallogr 41, 891–894 (2011). https://doi.org/10.1007/s10870-011-0044-4

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