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Structural Conformation of a Novel Piperidine-4-One Derivative: 1-Acryloyl-3-Methyl-2,6-Dip-Tolylpiperidine-4-One

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Abstract

The novel 3-methyl-2,6-dip-toylpiperidine-4-one was acylated by 3-chloropropanoychloride and subjected for dehydrohalogenation. The synthesized compound was characterized by spectroscopic techniques and finally confirmed by X-ray diffraction studies. The molecule crystallizes in the monoclinic crystal class in the space group C 2/c with cell parameters a = 18.538(2) Å, b = 9.9050(1) Å, c = 22.954(2) Å, β = 94.486(8)° and Z = 8. The piperidine ring adopts a twist boat conformation.

Graphical Abstract

The title compound was synthesized by acylation of 3-methyl-2,6-dip-tolylpiperidin-4-one followed by dehydrohalogenation and recrystalisation in ethanol. The molecule crystallizes in the monoclinic crystal class in the space group C2/c with cell parameters a = 18.538(2)Å, b = 9.9050(1) Å, c = 22.954(2) Å, β =  94.486(8)° and Z = 8. The heterocyclic ring adopts a twisted boat conformation.

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Acknowledgments

The authors are grateful to DST and Government of India project SP/I2/FOO/93 and University of Mysore, Mysore for financial assistance.

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Authors and Affiliations

  1. Department of Studies in Physics, University of Mysore, Manasagangotri, Mysore, 570 006, India

    B. N. Lakshminarayana, T. N. Mahadeva Prasad, M. A. Sridhar & J. Shashidhara Prasad

  2. Department of Studies in Chemistry, University of Mysore, Mysore, 570 006, India

    C. R. Gnanendra, Nagaraja Naik & D. Chenne Gowda

Authors
  1. B. N. Lakshminarayana
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  2. C. R. Gnanendra
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  3. T. N. Mahadeva Prasad
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  4. M. A. Sridhar
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  5. Nagaraja Naik
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  6. D. Chenne Gowda
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  7. J. Shashidhara Prasad
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Correspondence to J. Shashidhara Prasad.

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Lakshminarayana, B.N., Gnanendra, C.R., Prasad, T.N.M. et al. Structural Conformation of a Novel Piperidine-4-One Derivative: 1-Acryloyl-3-Methyl-2,6-Dip-Tolylpiperidine-4-One. J Chem Crystallogr 40, 686–690 (2010). https://doi.org/10.1007/s10870-010-9722-x

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  • DOI: https://doi.org/10.1007/s10870-010-9722-x

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