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The effects of temperature on the dynamics of the biological neural network

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Abstract

The nerve cells are responsible for transmitting messages through the action potential, which generates electrical stimulation. One of the methods and tools of electrical stimulation is infrared neural stimulation (INS). Since the mechanism of INS is based on electromagnetic radiation, it explains how a neuron is stimulated by the heat distribution which is generated by the laser. The present study is focused on modeling and simulating the conditions in which deformed temperature related to the Hodgkin and Huxley model can be effectively and safely used to activate the neurons, the fires of which depend on temperature. The results explain ionic channels in the single and network neurons, which behave differently when thermal stimulation is applied to the cell. It causes the variation of the pattern of the action potential in the Hodgkin-Huxley (HH) model. The stability of the phase-plane at high temperatures has lower fluctuations than at low temperatures, so the channel gates open and close faster. The behavior of these channels under various membrane temperatures shows that the firing rate increases with temperature. Also, the domain of the spikes reduces and the spikes occur faster with increasing temperature.

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Authors and Affiliations

  1. The Department of Theoretical Physics, Faculty of Physics, University of Tabriz, Tabriz, Iran

    Mohammad B Jabbari & Mahdi Rezaei Karamati

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  1. Mohammad B Jabbari
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  2. Mahdi Rezaei Karamati
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Correspondence to Mahdi Rezaei Karamati.

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Jabbari, M.B., Karamati, M.R. The effects of temperature on the dynamics of the biological neural network. J Biol Phys 48, 111–126 (2022). https://doi.org/10.1007/s10867-021-09598-1

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