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The distinct longitudinal impact of pain catastrophizing on pain interference among youth living with sickle cell disease and chronic pain

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Abstract

Youth living with chronic sickle cell disease (SCD) pain are at risk for psychosocial distress and high levels of pain catastrophizing that contribute to functional impairment. This study aimed to identify the unique long-term impact of pain catastrophizing on pain impairment among youth with SCD. Youth with chronic SCD pain (N = 63, 10–18 years old, 58.3% female, 95.1% Black or African American) were recruited within comprehensive SCD clinics and completed a battery of measures at baseline and 4-months follow-up. A linear hierarchical regression examined baseline demographic and clinical characteristics (child SCD genotype, age, and average pain intensity), psychosocial functioning (anxiety, depression), and pain catastrophizing as predictors of pain interference at 4-months follow-up. Pain catastrophizing was the only unique predictor of pain interference at 4-months follow-up. Among youth with chronic SCD pain, pain catastrophizing warrants greater consideration as an important predictor that influences pain management and overall functioning.

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  1. Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, 515 N Crossville Rd, Roswell, GA, 30075, USA

    Mallory B. Schneider, Alison Manikowski, Carlton Dampier & Soumitri Sil

  2. Emory University School of Medicine, Atlanta, USA

    Mallory B. Schneider, Alison Manikowski, Lindsey Cohen, Carlton Dampier & Soumitri Sil

  3. Department of Psychology, Georgia State University, Atlanta, USA

    Lindsey Cohen

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Schneider, M.B., Manikowski, A., Cohen, L. et al. The distinct longitudinal impact of pain catastrophizing on pain interference among youth living with sickle cell disease and chronic pain. J Behav Med 45, 622–631 (2022). https://doi.org/10.1007/s10865-021-00280-4

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