Abstract
Ectopic expression of coupling factor B in animal cells resulted in altered mitochondrial morphology. Cells expressing factor B fused to green fluorescent protein (GFP) contained fragmented, balloon-shaped or thinned, filamentous mitochondria, terminating at one end with balloon-like structures. Ultrastructural analysis using transmission electron microscopy revealed changes in the organization of mitochondrial cristae in cells expressing factor B-GFP fusion protein.
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References
Amutha B, Gordon DM, Gu Y, Pain D (2004) Biochem J 381:19–23
Arselin G, Vaillier J, Salin B, Schaeffer J, Giraud MF, Dautant A, Brèthes D, Velours J (2004) J Biol Chem 279:40392–40399
Belogrudov GI (2002) Arch Biochem Biophys 406:271–274
Belogrudov GI (2006) Arch Biochem Biophys 451:68–78
Belogrudov GI (2007) Arch Biochem Biophys 461:95–103
Belogrudov GI (2008) Arch Biochem Biophys 473:76–87
Belogrudov GI (2009) J Bioenerg Biomembr 41:137–143
Belogrudov GI, Hatefi Y (2002) J Biol Chem 277:6097–6103
Belogrudov GI, Tomich JM, Hatefi Y (1995) J Biol Chem 270:2053–2060
Belogrudov GI, Tomich JM, Hatefi Y (1996) J Biol Chem 271:20340–20345
Benard G, Rossignol R (2008) Antioxid Redox Signal 10:1313–1342
Beraud N, Pelloux S, Usson Y, Kuznetsov AV, Ronot X, Tourneur Y, Saks V (2009) J Bioenerg Biomembr 41:195–214
Berman SB, Chen YB, McCaffery JM, Rucker EB 3 rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM (2009) J Cell Biol 184:707–719
Chan DC (2006) Annu Rev Cell Dev 22:79–99
Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, Pedersen PL (2004) J Biol Chem 279:31761–31768
Collins TJ, Berridge MJ, Lipp P, Bootman MD (2002) EMBO J 21:1616–1627
de Brito OM, Scorrano L (2008) Nature 456:605–610
Dudkina NV, Heinemeyer J, Keegstra W, Boekema EJ, Braun HP (2005) FEBS Lett 579:5769–5772
Fillingame RH, Angevine CM, Dmitriev OY (2003) FEBS Lett 555:29–34
Griparic L, van der Wel NN, Orozco IJ, Peters PJ, van der Bliek AM (2004) J Biol Chem 279:18792–18798
Hatefi Y (1985) Annu Rev Biochem 54:1015–1069
Hong S, Pedersen PL (2008) Microbiol Mol Biol Rev 72:590–641
Junge W, Sielaff H, Engelbrecht S (2009) Nature 459:364–370
Kanazawa T, Zappaterra MD, Hasegawa A, Wright AP, Newman-Smith ED, Buttle KF, McDonald K, Mannella CA, van der Bliek AM (2008) PloS Genet 4:e1000022
Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL (2003) J Biol Chem 278:12305–12309
Kopecky J, Glaser E, Norling B, Ernster L (1981) FEBS Lett 131:208–212
Lam KW, Warshaw JB, Sanadi DR (1967) Arch Biochem Biophys 119:477–484
Lee JK, Belogrudov GI, Stroud RM (2008) Proc Natl Acad Sci USA 105:13379–13384
Lee CP, Ernster L (1965) Biochem Biophys Res Commun 18:523–529
Mannella CA (2008) Ann N Y Acad Sci 1147:171–179
Minauro-Sanmiguel F, Wilkens S, Garcia JJ (2005) Proc Natl Acad Sci USA 102:12356–12357
Pauleau AL, Galuzzi L, Scholz SR, Larochette N, Kepp O, Kroemer G (2008) Cell Death Differ 15:616–618
Paumard P, Vaillier J, Coulary B, Schaeffer J, Soubannier V, Mueller DM, Brèthes D, di Rago JP, Velours J (2002) EMBO J 21:221–230
Sanadi DR (1982) Biochim Biophys Acta 683:39–56
Schagger H, Pfeiffer K (2000) EMBO J 19:1777–1783
Stephenson G, Sanadi DR (1989) Biochem Int 19:1087–1094
Strauss M, Hofhaus G, Schroder RR, Kuhlbrandt W (2008) EMBO J 27:1154–1160
Thomas D, Bron P, Weinmann T, Dautant A, Giraud MF, Paumard P, Salin B, Cavalier A, Velours J, Brèthes D (2008) Biol Cell 100:591–601
Velours J, Dautant A, Salin B, Sagot I, Brethes D (2009) Int J Biochem Cell Biol 41:1783–1789
Vik SB, Long JC, Wada T, Zhang D (2000) Biochim Biophys Acta 1458:457–466
Wasilewski M, Scorrano L (2009) Trends Endocrinol Metab 20:287–294
Wittig I, Schagger H (2009) Biochim Biophys Acta 1787:672–680
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Belogrudov, G.I. Coupling factor B affects the morphology of mitochondria. J Bioenerg Biomembr 42, 29–35 (2010). https://doi.org/10.1007/s10863-009-9263-1
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DOI: https://doi.org/10.1007/s10863-009-9263-1