Journal of Biomolecular NMR

, 45:351 | Cite as

Aliasing in reduced dimensionality NMR spectra: (3,2)D HNHA and (4,2)D HN(COCA)NH experiments as examples

  • David Pantoja-Uceda
  • Jorge SantoroEmail author


Reduced dimensionality NMR spectra usually require very large spectral widths in the shared dimension. In this paper we show that aliasing can be introduced in reduced dimensionality NMR spectra either to decrease the acquisition time or increase the resolution of the experiments without losing information. The gains of introducing aliasing are illustrated with two examples, the (3,2)D HNHA and the (4,2)D HN(COCA)NH experiments. In both cases a reduction of the spectral width of more than 50% was possible.


Aliasing Reduced dimensionality HNHA HN(COCA)NH Proteins Resonance assignment 



This work was supported by project CTQ2008-00080 from the Spanish Ministerio de Ciencia e Innovación. D.P-U. was supported by a “Juan de la Cierva” contract from the Ministerio de Ciencia e Innovación.


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© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  1. 1.Instituto de Química Física Rocasolano, CSICMadridSpain

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