Skip to main content
Log in

Solution structure of the human Tax-interacting protein-1

  • NMR Structure Note
  • Published:
Journal of Biomolecular NMR Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  • Alewine C, Olsen O, Wade JB, Welling PA (2006) TIP-1 has PDZ scaffold antagonist activity. Mol Biol Cell 17:4200–4211

    Article  Google Scholar 

  • Banerjee M, Huang C, Marquez J, Mohanty S (2008) Probing the structure and function of human glutaminase-interacting protein: a possible target for drug design. Biochemistry 47:9208–9219

    Article  Google Scholar 

  • Birrane G, Chung J, Ladias JAA (2003) Novel mode of ligand recognition by the Erbin PDZ domain. J Biol Chem 278:1399–1402

    Article  Google Scholar 

  • Brünger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kuntstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simoson T, Warren GL (1998) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr Sect D: Biol Crystallogr 55:905–921

    Article  Google Scholar 

  • Cornilescu G, Delaglio F, Bax A (1999) Protein backbone angle restraints from searching a database for chemical shift and sequence homology. J Biomol NMR 13:289–302

    Article  Google Scholar 

  • Delaglio F, Grzesiek S, Vuister G, Zhu G, Pfeifer J, Bax A (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6:277–293

    Article  Google Scholar 

  • Dhulesia A, Gsponer J, Vendruscolo M (2008) Mapping of two networks of residues that exhibit structural and dynamical changes upon binding in a PDZ domain protein. J Am Chem Soc 130:8931–8939

    Article  Google Scholar 

  • Doyle DA, Lee A, Lewis J, Kim E, Sheng M, MacKinnon R (1996) Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell 85:1067–1076

    Article  Google Scholar 

  • Güntert P, Mumenthaler C, Wüthrich K (1997) Torsion angle dynamics for NMR structure calculation with the new program DYANA. J Mol Biol 273:283–298

    Article  Google Scholar 

  • Johnson BA, Blevins RA (1994) NMRView: a computer program for the visualization and analysis of NMR data. J Biomol NMR 4:603–614

    Article  Google Scholar 

  • Kanamori M, Sandy P, Marzinotto S, Benetti R, Kai C, Hayashizaki Y, Schneider C, Suzuki H (2003) The PDZ protein Tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells. J Biol Chem 278:38758–38764

    Article  Google Scholar 

  • Laskowski RA, Rullmann JA, MacArthur MW, Kaptein R, Thornton JW (1996) AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J Biomol NMR 8:477–486

    Article  Google Scholar 

  • Liu J, Zhang J, Yang Y, Huang H, Shen W, Hu Q, Wang X, Wu J, Shi Y (2008) Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor. Protein Sci 17:1003–1014

    Article  Google Scholar 

  • Marley J, Lu M, Bracken C (2001) A method for efficient isotopic labeling of recombinant proteins. J Biomol NMR 20:71–75

    Article  Google Scholar 

  • Nederveen A, Doreleijers JF, Vranken W, Miller Z, Spronk CA, Nabuurs SB, Güntert P, Livny M, Markley JL, Nilges M, Ulrich EL, Kaptein R, Bonvin AM (2005) RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank. Proteins 59:662–672

    Article  Google Scholar 

  • Olalla L, Aledo JC, Bannenberg G, Márquez J (2001) The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins. FEBS Lett 488:116–122

    Article  Google Scholar 

  • Reynaud C, Fabre S, Jalinot P (2000) The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element. J Biol Chem 275:33962–33968

    Article  Google Scholar 

  • Rousset R, Fabre S, Desbois C, Bantignies F, Jalinot P (1998) The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins. Oncogene 16:643–654

    Article  Google Scholar 

  • Zhang J, Yan X, Shi C, Yang X, Guo Y, Tian C, Long J, Shen Y (2008) Structural basis of β-catenin recognition by Tax-interacting protein-1. J Mol Biol 384:255–263

    Article  Google Scholar 

  • Zhang Y, Appleton BA, Weismann C, Lau T, Costa M, Hannoush RN, Sidhu SS (2009) Inhibition of Wnt signaling by dishevelled PDZ peptides. Nat Chem Biol 5:217–219

    Article  Google Scholar 

Download references

Acknowledgments

We thank Robert Griffin and Tony Bielecki for NMR access at the MIT/Harvard Center for Magnetic Resonance (funded by NIH grant EB-002026), and George Whitesides, Harvard University, for access to ITC instrumentation. This work was supported by grants GM065520, DK062162, and AG021964 from the National Institutes of Health, DAMD170210300, DAMD170310563, W81XWH0510622, and W81XWH0710178 from the US Department of Defense, a grant from the Dystonia Medical Research Foundation, and the Temple Discovery Award TLL035927 from the Alzheimer’s Association to J.A.A.L.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to John A. A. Ladias.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Durney, M.A., Birrane, G., Anklin, C. et al. Solution structure of the human Tax-interacting protein-1. J Biomol NMR 45, 329–334 (2009). https://doi.org/10.1007/s10858-009-9361-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10858-009-9361-8

Keywords

Navigation