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The application of 3D-printed titanium mesh in maxillary tumor patients undergoing total maxillectomy

  • Clinical Applications of Biomaterials
  • Original Research
  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

Objective

To evaluate the clinical outcomes of reconstruction of maxillary class III defect using 3D-printed titanium mesh.

Methods

Twelve patients with maxillary class III defect from April 2015 to December 2016 were retrospectively studied. A 3D individualized maxillary stereo model based on mirror images of the unaffected maxilla was obtained to fabricate an anatomically adapted titanium mesh using computer-assisted design and manufacture. The individual titanium mesh was inserted into the maxillary class III defect after total maxillectomy. The incidence of postoperative complications was evaluated. The postoperative orbital volume and protrusion degree of eye were measured.

Results

All patients were satisfied with their postoperative facial symmetry, without developing diplopia or endophthalmos. The postoperative orbital volumes were 26.41 ± 0.52 mL on the affected side and 26.55 ± 0.45 mL on the unaffected side. The postoperative protrusion degrees of affected and unaffected eyes were 16.21 ± 0.48 and 16.82 ± 0.79 mm, respectively. Titanium mesh exposure was observed in 2 patients and mild limitation of mouth opening was observed in 4 patients who underwent postoperative radiotherapy.

Conclusion

Reconstruction of maxillary class III defect with 3D-printed titanium mesh can achieve successful clinical outcomes, which recovered orbital volume and protrusion degree of eye.

Twelve patients with maxillary class III defect were satisfied with their postoperative facial symmetry, without developing diplopia or endophthalmos. We investigated that reconstruction of maxillary class III defect with 3D-printed titanium mesh can achieve successful clinical outcomes.

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Funding

This study was supported by the National Natural Science Foundation of China (81500872), Natural Science Foundation of Jiangsu Province (BK20161389), Young Medical Talent Foundation of Jiangsu Province (QNRC2016906), and Six talent peaks project in Jiangsu Province (2016-WSW-093), National Postdoctoral Foundation (2016M593040).

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Author notes

  1. These authors contributed equally: Bing-yao Liu, Gang Cao

Authors and Affiliations

  1. Department of Stomatology, Jinling Hospital, Medical School of Nanjing University, 305 Zhongshan East Road, Nanjing, 210002, Jiangsu, PR China

    Bing-yao Liu, Gang Cao, Zhen Dong, Wei Chen & Jin-ke Xu

  2. Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, PR China

    Ting Guo

Authors
  1. Bing-yao Liu
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  2. Gang Cao
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  3. Zhen Dong
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  4. Wei Chen
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  5. Jin-ke Xu
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Correspondence to Ting Guo.

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Liu, By., Cao, G., Dong, Z. et al. The application of 3D-printed titanium mesh in maxillary tumor patients undergoing total maxillectomy. J Mater Sci: Mater Med 30, 125 (2019). https://doi.org/10.1007/s10856-019-6326-7

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  • DOI: https://doi.org/10.1007/s10856-019-6326-7

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