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Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications

Journal of Materials Science: Materials in Medicine volume 29, Article number: 163 (2018) Cite this article

Abstract

Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the invading pathogens. In this paper, we report the development of a novel electrospun polyvinyl alcohol (PVA) membrane containing biosynthesized silver nanoparticle (bAg) for wound dressing applications. Plant extract from a medicinal plant Mimosa pudica was utilized for the synthesis of bAg. Synthesized bAg were characterized by Ultraviolet-Visible (UV) Spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR). The morphology of bAg was obtained from Transmission Electron Microscopy (TEM) and found that they were spherical in morphology with average particle size 7.63 ± 1.2 nm. bAg nanoparticles incorporated PVA membranes were characterized using several physicochemical techniques such as Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Spectroscopy (EDS) and X-Ray Diffraction (XRD) analysis. Experimental results confirmed the successful incorporation of bAg in PVA fibers. PVA nanofiber membranes incorporated with bAg showed good mechanical strength, excellent exudate uptake capacity, antibacterial activity, blood compatibility and cytocompatibility.

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Funding

This article was made possible by the NPRP9-144-3-021 grant funded by Qatar national Research Fund (a part of Qatar Foundation). The statements made here are totally responsibility of authors.

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Authors and Affiliations

  1. Department of Mechanical and Industrial Engineering, College of Engineering, Qatar University, Doha, 2713, Qatar

    Robin Augustine & Anwarul Hasan

  2. Biomedical Research Centre, Qatar University, Doha, 2713, Qatar

    Robin Augustine, Anwarul Hasan & Ala-Eddin Al Moustafa

  3. International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, 686 560, India

    V. K Yadu Nath, Jince Thomas, Nandakumar Kalarikkal & Sabu Thomas

  4. Department of Chemistry, Bishop Kurialacherry College for Women, Amalagiri, Kottayam, Kerala, 686561, India

    Anitha Augustine

  5. School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, 686 560, India

    Nandakumar Kalarikkal

  6. College of Medicine, Qatar University, Doha, 2713, Qatar

    Ala-Eddin Al Moustafa

  7. School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, 686 560, India

    Sabu Thomas

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  1. Robin Augustine
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Augustine, R., Hasan, A., Yadu Nath, V.K. et al. Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications. J Mater Sci: Mater Med 29, 163 (2018). https://doi.org/10.1007/s10856-018-6169-7

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  • DOI: https://doi.org/10.1007/s10856-018-6169-7