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Bacterial adhesion on biomedical surfaces covered by yttria stabilized zirconia

  • Biomaterials Synthesis and Characterization
  • Original Research
  • Published:
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Abstract

The aim of this study was to compare the bacterial adhesion of Staphylococcus spp. on Ti–6Al–4V with respect to Ti–6Al–V modified alloys with a set of Cubic yttria stabilized zirconia (YSZ) and Ag-YSZ nanocomposite films. Silver is well known to have a natural biocidal character and its presence in the surface predicted to enhance the antimicrobial properties of biomedical surfaces. Microbial adhesion tests were performed using collection strains and twelve clinical strains of Staphylococcus aureus and Staphylococcus epidermidis. The adherence study was performed using a previously published protocol by Kinnari et al. Both collection strains and clinical isolates have shown lower bacterial adhesion to materials modified with respect to the alloy Ti–6Al–4V and the modification with silver reduced the bacterial adhesion for most of all the strains studied. Moreover the percentage of dead bacteria have been evaluated, demonstrating increased proportion of dead bacteria for the modified surfaces. Nanocrystalline silver dissolves releasing both Ag+ and Ag0 whereas other silver sources release only Ag+. We can conclude that YSZ with nanocrystalline silver coating may lead to diminished postoperative infections and to increased corrosion and scratch resistance of YSZ incorporating alloys Ti–6Al–4V.

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Acknowledgments

This study was realized thanks to a help of the Program CONSOLIDER-INGENIO 2010 FUNCOAT-CSD2008-00023 and by a Grant from the Spanish MINECO (MAT2013-48224-C2-2-R).

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Authors and Affiliations

  1. Department of Clinical Microbiology, IIS-Fundación Jiménez Díaz, Ave Reyes Católicos 2, 28040, Madrid, Spain

    Ramón Pérez-Tanoira, Concepción Pérez-Jorge & Jaime Esteban

  2. Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

    Ramón Pérez-Tanoira & Teemu J. Kinnari

  3. Institut Jean Lamour, UMR7198, Université de Lorraine, 54011, Nancy, France

    David Horwat

  4. Department of Traumatology and Orthopaedic, IIS-La Paz, 28046, Madrid, Spain

    Enrique Gómez-Barrena

  5. Centre de Compétences en Microscopies Electroniques et Microsondes (CC-MEM), Institut Jean Lamour, Parc de Saurupt, CS 50840, 54011, Nancy, France

    Sylvie Migot

Authors
  1. Ramón Pérez-Tanoira
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  2. David Horwat
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  3. Teemu J. Kinnari
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  4. Concepción Pérez-Jorge
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  5. Enrique Gómez-Barrena
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  6. Sylvie Migot
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  7. Jaime Esteban
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Corresponding author

Correspondence to Ramón Pérez-Tanoira.

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Pérez-Tanoira, R., Horwat, D., Kinnari, T.J. et al. Bacterial adhesion on biomedical surfaces covered by yttria stabilized zirconia. J Mater Sci: Mater Med 27, 6 (2016). https://doi.org/10.1007/s10856-015-5625-x

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  • DOI: https://doi.org/10.1007/s10856-015-5625-x

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