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A homogenous CS/NaCMC/n-HA polyelectrolyte complex membrane prepared by gradual electrostatic assembling

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Abstract

A homogenous membrane composed of chitosan (CS), sodium carboxymethyl cellulose (NaCMC) and nano hydroxyapatite (n-HA) was prepared by a gradual electrostatic assembling (GEA) method. The physical and chemical properties of the membranes with different n-HA contents and CS/NaCMC ratios were characterized by Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and mechanical test. The schematic formation mechanism of the membrane was discussed. The results show that GEA is an effective method to prepare the polyelectrolyte complex (PEC) membrane, in which oppositely charged CS-NaCMC polysaccharides can assemble mildly and gradually through electrostatic interaction to form the membrane framework, while the filled n-HA crystals can regulate the structure stability of the composite membrane. The optimum preparation condition for the PEC membrane can be fixed to a content of 60 wt% n-HA, an equivalent amount of CS to NaCMC and a drying temperature of 60°C. The PEC membrane may have good prospect for guided bone regeneration.

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Acknowledgments

This work is supported by China 973 fund (No. 2007CB936102) and China–Netherlands Program Strategic Alliances (No. 2008DFB50120).

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Authors and Affiliations

  1. Research Center for Nano Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu, 610064, People’s Republic of China

    Hong Jiang, Yi Zuo, Lin Cheng, Hongli Wang, Aiqun Gu & Yubao Li

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  1. Hong Jiang
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  2. Yi Zuo
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  3. Lin Cheng
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  4. Hongli Wang
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  5. Aiqun Gu
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  6. Yubao Li
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Correspondence to Yi Zuo or Yubao Li.

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Jiang, H., Zuo, Y., Cheng, L. et al. A homogenous CS/NaCMC/n-HA polyelectrolyte complex membrane prepared by gradual electrostatic assembling. J Mater Sci: Mater Med 22, 289–297 (2011). https://doi.org/10.1007/s10856-010-4195-1

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  • DOI: https://doi.org/10.1007/s10856-010-4195-1

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