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Effect of strontium-containing hydroxyapatite bone cement on bone remodeling following hip replacement

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An Erratum to this article was published on 13 March 2010

Abstract

It is uncertain whether the use of bioactive bone cement has any beneficial effect on local bone adaptation following hip replacement. In this study, twelve goats underwent cemented hip hemiarthroplasty unilaterally, with either PMMA bone cement or strontium-containing hydroxyapatite (Sr-HA) bioactive bone cement. Nine months later, the femoral cortical bones at different levels were analyzed by microhardness testing and micro-CT scanning. Extensive bone remodeling was found at proximal and mid-levels in both PMMA and Sr-HA groups. However, with regard to the differences of bone mineral density, cortical bone area and bone hardness between implanted and non-implanted femur, less decreases were found in Sr-HA group than PMMA group at proximal and mid-levels, and significant differences were shown for bone area and hardness at proximal level. The results suggested that the use of Sr-HA cement might alleviate femoral bone remodeling after hip replacement.

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Acknowledgements

This project was partially supported by Fujian Young Talent Project (2007F3040).

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Authors and Affiliations

  1. Department of Rehabilitation Medicine, Fujian Medical University, Fuzhou, 350004, China

    Guo X. Ni

  2. Department of Orthopaedic Surgery, No. 1 Affiliated Hospital, Fujian Medical University, Fuzhou, China

    Jian H. Lin

  3. Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, Hong Kong

    Peter K. Y. Chiu, Zhao Y. Li & William W. Lu

Authors
  1. Guo X. Ni
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  2. Jian H. Lin
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  3. Peter K. Y. Chiu
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  4. Zhao Y. Li
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  5. William W. Lu
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Corresponding authors

Correspondence to Guo X. Ni or William W. Lu.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s10856-010-4033-5

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Ni, G.X., Lin, J.H., Chiu, P.K.Y. et al. Effect of strontium-containing hydroxyapatite bone cement on bone remodeling following hip replacement. J Mater Sci: Mater Med 21, 377–384 (2010). https://doi.org/10.1007/s10856-009-3866-2

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  • DOI: https://doi.org/10.1007/s10856-009-3866-2

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