In this paper, different organic–inorganic hybrid materials based in the CaO–SiO2–poly(dimethyl siloxane) PDMS system have been characterised by means of nanoindentation and their static mechanical properties (Young’s modulus, and hardness) have been investigated. These mechanical properties have been discussed in relation to the chemical composition and structure of the different hybrid materials. Besides, the mechanical behaviour of hybrid materials is visco-elastic and it therefore presents phenomena of creep that will be influenced by the temperature of the mechanical test; undoubtedly, a temperature of 37°C accelerates the processes of creep.