Skip to main content
SpringerLink
Log in

Silicon-substituted hydroxyapatite composite coating by using vacuum-plasma spraying and its interaction with human serum albumin

  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

The incorporation of silicon can improve the bioactivity of hydroxyapatite (HA). Silicon-substituted HA (Ca10(PO4)6−x (SiO4) x (OH)2−x , Si-HA) composite coatings on a bioactive titanium substrate were prepared by using a vacuum-plasma spraying method. The surface structure was characterized by using XRD, SEM, XRF, EDS and FTIR. The bond strength of the coating was investigated and XRD patterns showed that Ti/Si-HA coatings were similar to patterns seen for HA. The only different XRD pattern was a slight trend toward a smaller angle direction with an increase in the molar ratio of silicon. FTIR spectra showed that the most notable effect of silicon substitution was that –OH group decreased as the silicon content increased. XRD and EDS elemental analysis indicated that the content of silicon in the coating was consistent with the silicon-substituted hydroxyapatite used in spraying. A bioactive TiO2 coating was formed on an etched surface of Ti, and the etching might improve the bond strength of the coatings. The interaction of the Ti/Si-HA coating with human serum albumin (HSA) was much greater than that of the Ti/HA coating. This might suggest that the incorporation of silicon in HA can lead to significant improvements in the bioactive performance of HA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Suchanek W, Yoshimura M. Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants. J Mater Res. 1998;13:94–117.

    Article  ADS  CAS  Google Scholar 

  2. Sfidhar TM, Mudala UK, Subbaiyan M. Preparation and characterization of electrophoretically deposited hydroxyapatite coating on type 316L stainless steel. Corr Sci. 2003;45:237–52. doi:10.1016/S0010-938X(02)00091-4.

    Article  Google Scholar 

  3. Zhitomirsky I, Galor L. Electrophoretic deposition of hydroxyapatite. J Mater Med. 1997;8:213–9.

    Article  CAS  Google Scholar 

  4. Balas F, Perez PJ, Vallet RM. In vitro bioactivity of silicon-substituted hydroxyapatites. Biomaterials. 2003;24:3203–9.

    Google Scholar 

  5. Tang XL, Xiao XF, Liu RF. Structural characterization of silicon-substituted hydroxyapatite synthesized by a hydrothermal method. Mater Lett. 2005;59:3841–6. doi:10.1016/j.matlet.2005.06.060.

    Article  CAS  Google Scholar 

  6. Thian ES, Huang J, Best SM, Barber ZH. Silicon-substituted hydroxyapatite: the next generation of bioactive coatings. Mater Sci Eng C. 2007;27:251–6. doi:10.1016/j.msec.2006.05.016.

    Article  CAS  Google Scholar 

  7. Suzuki K, Yumura T, Mizuguchi M, et al. Apatite-silica gel composite materials prepared by a new alternate soaking process. J Sol–Gel Sci Technol. 2001;21:55–63.

    Article  CAS  Google Scholar 

  8. Mondragon CZ, Vargas GG. Electrophoretic deposition of hydroxyapatite submicron particles at high voltages. Mater Lett. 2004;58:1336–9. doi:10.1016/j.matlet.2003.09.024.

    Article  Google Scholar 

  9. Junichi HA, Yuki A, Kiyoshi K. Fabrication of highly ordered macroporous apatite coating onto titanium by electrophoretic deposition method. Solid State Ion. 2004;172:331–4. doi:10.1016/j.ssi.2004.02.046.

    Article  Google Scholar 

  10. Wei M, Ruys AJ, Swain MV. Interfacial bond strength of electrophoretically deposited hydroxyapatite coatings on metals. J Mater Sci: Mater Med. 1999;10:401–9. doi:10.1023/A:1008923029945.

    Article  CAS  Google Scholar 

  11. Niwa M, Wei L, Sato I. The adsorptive property of hydroxyapatite to albumin dextrin and lipids. Biomed Mater Eng. 1999;9:163–9.

    PubMed  CAS  Google Scholar 

  12. Tanizawa Y, Suzuki T. X-ray photoelectron spectroscopy study of silicate-containing apatite. Phosphorus Res Bull. 1994;4:83–8.

    CAS  Google Scholar 

  13. Gibson IR, Best SM, Bonfield W. Chemical characterization of silicon-substituted hydroxyapatite. J Biomed Mater Res. 1999;4:422–8. doi:10.1002/(SICI)1097-4636(19990315)44:4<422::AID-JBM8>3.0.CO;2-#.

    Article  Google Scholar 

  14. Le Ventouri TH, Bunaciu CE, Perdikatsis V. Neutron powder difraction studies of silicon-substituted hydroxyapatite. Biomaterials. 2003;24:4205–421. doi:10.1016/S0142-9612(03)00333-8.

    Article  CAS  Google Scholar 

  15. Tao W-s, Li W, Jiang Y-M. The basic of protein molecules. 2nd ed. Beijing: Higher Education Press; 1995.

    Google Scholar 

  16. Yin G, Zhan J, Liu Z. Characterization of the adsorption of human serum albumin on hydroxylapatite. Chem J Chin Univ. 2002;22:771–5. J.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Material Science and Engineering, Shjiazhuang Railway Institute, No.17 North 2nd-Ring East Road, Shijiazhuang, 050043, Hebei Province, China

    Feng-juan Xiao, Lei Peng, Ying Zhang & Li-jiang Yun

Authors
  1. Feng-juan Xiao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lei Peng
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ying Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Li-jiang Yun
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Feng-juan Xiao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Xiao, Fj., Peng, L., Zhang, Y. et al. Silicon-substituted hydroxyapatite composite coating by using vacuum-plasma spraying and its interaction with human serum albumin. J Mater Sci: Mater Med 20, 1653–1658 (2009). https://doi.org/10.1007/s10856-009-3723-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10856-009-3723-3

Keywords

Search

Navigation