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Preparation of tricalcium phosphate/calcium pyrophosphate structures via rapid prototyping

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Abstract

Custom made tricalcium phosphate/calcium pyrophosphate bone substitutes with a well-defined architecture were fabricated in this study using 3D powder printing with tricalcium phosphate (TCP) powder and a liquid phase of phosphoric acid. The primary formed matrix of dicalcium phosphate dihydrate (DCPD, brushite) was converted in a second step to calcium pyrophosphate (CPP) by heat treatment in the temperature range 1,100–1,300°C. The structures exhibited compressive strengths between 0.8 MPa and 4 MPa after sintering at 1,100–1,250°C, higher strengths were obtained by increasing the amount of pyrophosphate formed in the matrix due to a post-hardening regime prior sintering as well as by the formation of a glass phase from TCP and calcium pyrophosphate above 1,280°C, which resulted in a strong densification of the samples and compressive strength of >40 MPa.

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Authors and Affiliations

  1. Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, 97070, Wurzburg, Germany

    Uwe Gbureck, Tanja Hölzel & Isabell Biermann

  2. Faculty of Dentistry, McGill University, Strathcona Anatomy and Dentistry Building, 3640 University St., Montreal, QC, Canada, H3A 2B2

    Jake E. Barralet

  3. Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK

    Liam M. Grover

Authors
  1. Uwe Gbureck
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  2. Tanja Hölzel
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  3. Isabell Biermann
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  4. Jake E. Barralet
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  5. Liam M. Grover
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Correspondence to Uwe Gbureck.

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Gbureck, U., Hölzel, T., Biermann, I. et al. Preparation of tricalcium phosphate/calcium pyrophosphate structures via rapid prototyping. J Mater Sci: Mater Med 19, 1559–1563 (2008). https://doi.org/10.1007/s10856-008-3373-x

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  • DOI: https://doi.org/10.1007/s10856-008-3373-x

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