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Journal of Materials Science: Materials in Medicine

, Volume 18, Issue 11, pp 2137–2143 | Cite as

Mechanical properties of bovine hydroxyapatite (BHA) composites doped with SiO2, MgO, Al2O3, and ZrO2

  • Faik Nüzhet Oktar
  • Simeon Agathopoulos
  • L. Sevgi Ozyegin
  • Oguzhan Gunduz
  • Nermin Demirkol
  • Yahya Bozkurt
  • Serdar Salman
Article

Abstract

Biologically derived hydroxyapatite from calcinated (at 850 °C) bovine bones (BHA) was doped with 5 wt% and 10 wt% of SiO2, MgO, Al2O3 and ZrO2 (stabilized with 8% Y2O3). The aim was to improve the sintering ability and the mechanical properties (compression strength and hardness) of the resultant BHA-composites. Cylindrical samples were sintered at several temperatures between 1,000 and 1,300 °C for 4 h in air. The experimental results showed that sintering generally occurs at 1,200 °C. The BHA–MgO composites showed the best sintering performance. In the BHA–SiO2 composites, extended formation of glassy phase occurred at 1,300 °C, resulting in structural degradation of the resultant samples. No sound reinforcement was achieved in the case of doping with Al2O3 and zirconia probably due to the big gap between the optimum sintering temperatures of BHA and these two oxides.

Keywords

Zirconia Y2O3 Compression Strength Bovine Spongiform Encephalopathy Extensive Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgements

This study was carried out with the financial support of the Turkish Republic Government Planning Organization in the framework of the Project “Manufacturing and Characterization of Electro-Conductive Bioceramics” with project number 2003 K120810. S. Agathopoulos gratefully acknowledges his financial support through the Project ENTER 04EP26 of the European Union and the Greek Secretariat of Research and Technology. SEM pictures were taken under supervision of Associate Professor Ahmet Capoglu from Gebze Institute of Technology. The authors thank to Associate Professor Dr. G. Goller from Istanbul Technical University for using the microhardness apparatus.

References

  1. 1.
    B. BEN-NISSAN, A. MILEV and R. VAGO, Biomaterials 25 (2004) 4971CrossRefGoogle Scholar
  2. 2.
    L. S. OZYEGIN, F. N. OKTAR, G. GOLLER, E. S. KAYALI and T. YAZICI, Mater. Lett. 58 (2004) 2605CrossRefGoogle Scholar
  3. 3.
    J. H. G. ROCHA, A. F. LEMOS, S. AGATHOPOULOS, P. VALEIRO, S. KANNAN, F. N. OKTAR and J. M. F. FERREIRA, Bone 37 (2005) 850CrossRefGoogle Scholar
  4. 4.
    F. N. OKTAR, Mater. Lett. 60 (2006) 2207CrossRefGoogle Scholar
  5. 5.
    S. AGATHOPOULOS, D. U. TULYAGANOV, P. A. A. P. MARQUES, M. C. FERRO, M. H. V. FERNANDES and R. N. CORREIA, Biomaterials 24 (2003) 1317CrossRefGoogle Scholar
  6. 6.
    http://www.innvista.com/default.htm, MineralsGoogle Scholar
  7. 7.
    J. W. REID, L. TUCK, M. SAYER, K. FARGO and J. A. HENDRY, Biomaterials 27 (2006) 2916CrossRefGoogle Scholar
  8. 8.
    S. K. KIM, J. H. LEE, Y. T. KIM, D. H. RIU, S. J. JUNG, Y. J. LEE, S. C. CHUNG and Y. H. KIM, Biomaterials 24 (2003) 1389CrossRefGoogle Scholar
  9. 9.
    E. BERTONI, A. BIGI, G. COJAZZI, M. GANDOLFI, S. PANZAVOLTA and N. ROVERI, J. Inorg. Biochem. 72 (1998) 29CrossRefGoogle Scholar
  10. 10.
    S. NI, L. CHOU and J. CHANG, Ceram. Int. 33 (2007) 83CrossRefGoogle Scholar
  11. 11.
    S. AGATHOPOULOS, D. U. TULYAGANOV, J. M. G. VENTURA, S. KANNAN, M. A. KARAKASSIDES and J. M. F. FERREIRA, Biomaterials 27 (2006) 1832CrossRefGoogle Scholar
  12. 12.
    W. CHENGTIE, C. JIANG, W. JUNJING, N. SIYU and Z. WANYIN, Biomaterials 26 (2005) 2925CrossRefGoogle Scholar
  13. 13.
    A. GOEL, D. U. TULYAGANOV, S. AGATHOPOULOS, M. J.RİBEİRO and J. M. F.FERREİRA, Ceram. Int. (2007) doi:10.1016/j.ceramint.2006.05.012Google Scholar
  14. 14.
    H.-W. KIM, Y.-H. KOH, S.-B. SEO and H.-E. KIM, Mater. Sci. Eng. C 23 (2003) 515Google Scholar
  15. 15.
    A. CHIBA, S. KIMURA, R. RAGHUKANDAN and Y. MORIZONO, Mater. Sci. Eng. A 350 (2003) 179CrossRefGoogle Scholar
  16. 16.
    F. N. OKTAR, Y. GENC, G. GOLLER, S. AGATHOPOULOS, D. U. TULYAGANOV, J. M. F. FERREIRA, E. S. KAYALI and S. SALMAN Key Eng. Mater. 284–286 (2005) 709Google Scholar
  17. 17.
    K. YOSHIDA, K. HASHIMOTO, Y. TODA, S. UDAGAWA and T. KANAZAWA, J. Eur. Ceram. Soc. 26 (2006) 515CrossRefGoogle Scholar
  18. 18.
    S. AGATHOPOULOS, P. NIKOLOPOULOS, A. SALOMONI, A. TUCCI and I. STAMENKOVIC, J. Mater. Sci. Mater. Med. 7 (1996) 629CrossRefGoogle Scholar
  19. 19.
    F. N. OKTAR, K. KESENCI and E. PISKIN, Int. J. Artif. Cells Blood Sub. Immob. Biotech. 27 (1999) 367Google Scholar
  20. 20.
    W. SUCHANEK, M. YASHIMA, M. KAKIHANA and M. YOSHIMURA, Biomaterials 18 (1997) 923CrossRefGoogle Scholar
  21. 21.
    Y. GENC, F. N. OKTAR, E. Z. ERKMEN, G. GOLLER, D. TOYKAN and H. HAYBAT, Key Eng. Mater. 264–268 (2004) 1961Google Scholar
  22. 22.
    H. GOKBAYRAK, Production of hydroxyapatite ceramics, M.S. Thesis. (Bogazici University, 1996)Google Scholar
  23. 23.
    S. GOREN, H. GOKBAYRAK and S. ALTINTAS, Key Eng. Mater. 264–268 (2004) 1949Google Scholar
  24. 24.
    G. GOLLER, F. N. OKTAR, S. AGATHOPOULOS, D. U. TULYAGANOV, J. M. F. FERREIRA, E. S. KAYALI and I. PEKER, J. Sol-Gel Sci. Techn. 37 (2006) 111CrossRefGoogle Scholar
  25. 25.
    F. N. OKTAR, M. R. DEMIRER, O. GUNDUZ, Y. GENC, S. AGATHOPOULOS, I. PEKER, L. S. OZYEGIN and S. SALMAN, Key Eng. Mater. 309–311 (2006) 49Google Scholar
  26. 26.
    S. AGATHOPOULOS, M. C. FERRO, J. Y. XU, J. M. OLIVEIRA, P. A. A. P. MARQUES, R. N. CORREIA and M. H. V. FERNANDES, Key Eng. Mater. 240–242 (2003) 217CrossRefGoogle Scholar
  27. 27.
    M. KNEPPER, S. MORICCA and B. K. MILTHORPE, Biomaterials 18 (1997)1523Google Scholar
  28. 28.
    Y.-M. KONG, C.-J. BAE, S.-H. LEE, H.-W. KIM and H.-E. KIM, Biomaterials 26 (2005) 509CrossRefGoogle Scholar
  29. 29.
    M. S. KHALIL, H. H. BEHERI and W. I. ABDEL FATTAH, Ceram. Int. 28 (2002) 451CrossRefGoogle Scholar
  30. 30.
    A. RAPACZ-KMITA, A. lOSARCZYK, Z. PASZKIEWICZ and C. PALUSZKIEWICZ, J. Mol. Struct. 704 (2004) 333CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Faik Nüzhet Oktar
    • 1
    • 2
  • Simeon Agathopoulos
    • 3
  • L. Sevgi Ozyegin
    • 4
  • Oguzhan Gunduz
    • 5
  • Nermin Demirkol
    • 6
  • Yahya Bozkurt
    • 5
  • Serdar Salman
    • 5
  1. 1.School of Engineering, Industrial Engineering DepartmentMarmara UniversityKadikoy, IstanbulTurkey
  2. 2.Vocational School of Health Related Professions, Radiology DepartmentMarmara UniversityUskudar, IstanbulTurkey
  3. 3.Materials Science and Engineering DepartmentIoannina UniversityIoanninaGreece
  4. 4.Vocational School of Health Related Professions, Dental Technology DepartmentMarmara UniversityIstanbulTurkey
  5. 5.School of Education, Materials Technology DepartmentMarmara UniversityKadikoy, IstanbulTurkey
  6. 6.Material Science and Engineering DepartmentGebze Institute of TechnologyGebze, KocaeliTurkey

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