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Preparation of porous hydroxyapatite with interconnected pore architecture

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Abstract

Since pore connectivity has significant effects on the biological behaviors of biomedical porous hydroxyapatite (PHA), the preparation of PHA with interconnected pore architecture is of great practical significance. In the present study, PHA with highly interconnected architecture was prepared via a simple burnout route with rod-like urea as the porogen. Microscopy and porosimetry data showed that the as-prepared PHA had open and interconnected pore structure with the average fenestration size of about 120 μm. Open pores occupied up to 98% of the total porosity. The compressive strength and modulus of the as-prepared PHA were respectively 1.3–7.6 MPa and 4.0–10.4 GPa.

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Acknowledgements

We thank the financial support from the National Natural Science Foundation of China (No. 20221603) and Chinese Academy of Sciences.

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Authors and Affiliations

  1. Multiphase Reaction Laboratory, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, P.R. China

    Hui Gang Zhang & Qingshan Zhu

  2. Graduate School of the Chinese Academy of Sciences, Beijing, 100039, P.R. China

    Hui Gang Zhang

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  1. Hui Gang Zhang
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  2. Qingshan Zhu
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Correspondence to Qingshan Zhu.

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Zhang, H.G., Zhu, Q. Preparation of porous hydroxyapatite with interconnected pore architecture. J Mater Sci: Mater Med 18, 1825–1829 (2007). https://doi.org/10.1007/s10856-007-3036-3

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  • DOI: https://doi.org/10.1007/s10856-007-3036-3

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