Skip to main content
SpringerLink
Log in

The interaction of the polyphenylacetylene surface with biological environments studied by XPS, RAIRS and biological tests

  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

A π-conjugated polymer, polyphenylacetylene or PPA, has been tested for its possible applications as biosensor or biomaterial. Protein adsorption was investigated by incubating PPA films in solutions of bovine serum albumin (BSA) dissolved in phosphate buffer (PBS) having increasing protein concentration. Investigations on the PPA films were carried out by means of two surface analysis techniques, X-ray photoelectron spectroscopy (XPS) and reflection-absorption infrared spectroscopy (RAIRS). Desorption of BSA from the PPA surface was also investigated.

Finally, the cytototoxicity of the PPA surface was checked by measuring viability and proliferation of lymphoma macrophages and SAOS osteoblasts grown in the presence of the polymer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. GRIFFITH, A. GLIDLE and J. M. COOPER Biosensors & Bioelectronics 11 (1996) 625.

    Article  CAS  Google Scholar 

  2. M. TROJANOWICZ, O. GESCHKE, T. KRAWCZYNSKI VEL KRAWCZYK and K. CAMMANN Sens. Actuat. B 28 (1995) 191.

    Article  Google Scholar 

  3. MU SHAOLIN, XUE HUAIGUO and QIAN BIDONG J. Electroanal. Chem. 34 (1991) 7.

    Article  Google Scholar 

  4. J. DEL NERO, D. S. GALVAO and B. LAKS Optical Materials 21 (2002) 461.

    Article  Google Scholar 

  5. S. GASPAR, K. HABERMULLER, E.CSOREGI and W. SCHUHMANN Sens. Actuat. B 72 (2001) 63.

    Article  Google Scholar 

  6. A. FURLANI, G. IUCCI, M.V. RUSSO, A. BEARZOTTI and A. D'AMICO Sens. Actuat. B 8 (1992) 123.

    Article  Google Scholar 

  7. A. BEARZOTTI, V. FOGLIETTI, G. POLZONETTI, G. IUCCI, A. FURLANI and M.V. RUSSO Mater. Sci. Eng. 340 (1996) 1.

    Article  Google Scholar 

  8. G. POLZONETTI, M.V. RUSSO, A. FURLANI and G. IUCCI Chem. Phys. Lett. 185 (1991) 105.

    Article  CAS  Google Scholar 

  9. C. SATRIANO, C. SCIFO and G. MARLETTA Nucl. Instr. and Meth. Phys. Res. B 166–167 (2000) 782.

    Article  Google Scholar 

  10. G. IUCCI, G. POLZONETTI, G. INFANTE and L. ROSSI Surf. Interf. Anal. 36 (2004) 724.

    Article  CAS  Google Scholar 

  11. C.D. TIDWELL, D.G. CASTENER, S. L. GOLLEDGE, B.D. RATNER, K. MEYER, B. HAGENHOFF and A. BENNINGHOVEN Surf. Interf. Anal. 31 (2001) 724.

    Article  CAS  Google Scholar 

  12. J. L. BONERT and T. A. HORBETT J Colloid Interf. Sci 111 (1986) 363.

    Article  Google Scholar 

  13. F. ZHANG, E. T. KANG, K. G. NEOH, P. WANG and K. L. TAN Biomaterials 23 (2002) 787.

    Article  CAS  Google Scholar 

  14. A. FURLANI, C. NAPOLETANO, M. V. RUSSO, A. CAMUS and N. MARSICH J. Polym. Sci.: Part A: Polym. Chem. 27 (1989) 75.

    Article  CAS  Google Scholar 

  15. G. POLZONETTI, M. V. RUSSO, J. Electron Spectrosc. Relat. Phenom. 60 (1992) R7.

    Article  Google Scholar 

  16. J. F. MOULDER, W. F. STICKLE, P. E. SOBOL and K. D. BOMBEN “Handbook of X-ray Photoelectron Spectroscopy” Physical Electronics Inc. eds. (Eden Prairie, Minnesota 1995).

  17. A. LEBUGLE, M. SUBIRADE and J. GUEGUEN Biochim. Biophys. Acta 1248 (1995) 107.

    Google Scholar 

  18. D. D. DELIGIANNI, N. KATSALA, S. LADAS, D. SOTIROPOULOU, J. AMEBEE and Y. F. MISSIRLIS Biomaterials 22 (2001) 1241.

    Article  CAS  Google Scholar 

  19. J. H. SCOFIELD, J. Electron Spectrosc. Relat. Phenom. 8 (1976) 129.

    Article  CAS  Google Scholar 

  20. C. D. TIDWELL, D. G. CASTNER, S. L. GOLLEDGE, B. D. RATNER, K. MEYER, B. HAGENHOFF and A. BENNINGHOVEN Surf. Interf. Anal. 31 (2001) 724.

    Article  CAS  Google Scholar 

  21. P. SEAH and W. A. DENCH Surf. Interf. Anal. 1 (1979) 30.

    Google Scholar 

  22. D. BENDEDOUCH and S. H. CHEN J. Phys. Chem. 87 (1983) 1473.

    Article  CAS  Google Scholar 

  23. L. FENG, C. Z. HU, and J. D. ANDRADE J. Colloid Interface Sci. 126 (1988) 650.

    Article  CAS  Google Scholar 

  24. D. C. CARTER and J. X. HO Adv. Protein Chem. 45 (1994) 153.

    Article  CAS  Google Scholar 

  25. J. F. FOSTER, in “Albumin Structure, Function and Uses” edited by V. M. Rosenoer, M. Oratz, and M. A. Rothschild, pp. 53–84. (Pergamon, Oxford, 1977).

    Google Scholar 

  26. J. B. LHOEST, E. DETRAIT, P. VAN DEN BOSCH DE AGUILAR and P. BERTRAND J. Biomed. Mater. Res. 41 (1998) 95.

    Article  CAS  Google Scholar 

  27. H. M. KOWALCZYNSKA, M. NOWAK-WYRZYKOWSKA, J. DOBKOWSKI, R. KOLOS, J. KAMINSKI, A.MAKOWSKA-CYNKA and E. MARCINIAK J. Biomed. Mater. Res. 61 (2002) 260.

    Article  CAS  Google Scholar 

  28. D. O. H. TEARE, N. EMMISON, C. TON-THAT and R. H. BRADLEY Langmuir 16 (2000) 2818.

    Article  CAS  Google Scholar 

  29. B. W. CALLEN, R. N. S. SODHI, R. M. SHELTON and J. E. DAVIES J. Biomed. Mater. Res. 27 (1993) 851.

    Article  CAS  Google Scholar 

  30. M. HENRY and P. BERTRAND Surf. Interf. Anal. 36 (2004) 729.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dipartimento di Fisica E. Amaldi, Universit à “Roma Tre”, Unità INFM, INSTM, and CISDiC, Via della Vasca Navale 84, 00146, Roma

    G. Iucci, L. Rossi & G. Polzonetti

  2. Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Università di Roma “Tor Vergata”, Via Montpellier 1, 00133, Roma

    N. Rosato, I. Savini & G. Duranti

Authors
  1. G. Iucci
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Rossi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Rosato
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. I. Savini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. Duranti
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. G. Polzonetti
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to G. Iucci.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Iucci, G., Rossi, L., Rosato, N. et al. The interaction of the polyphenylacetylene surface with biological environments studied by XPS, RAIRS and biological tests. J Mater Sci: Mater Med 17, 779–787 (2006). https://doi.org/10.1007/s10856-006-9835-0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10856-006-9835-0

Keywords

Search

Navigation