Abstract
A highly porous T{i}6Al4V with interconnected porous structure has been developed in our previous study. By using a so-called “Multiple coating” technique, the porous T{i}6Al4V can be tailored to resemble cancellous bone in terms of porous structure and mechanical properties. A thin layer of T{i}6Al4V slurry was coated on the struts of base porous T{i}6Al4V to improve the pore structure. After two additional coating, pore sizes ranged from 100 μm to 700 μm, and the porosity was decreased from ∼90% to ∼ 75%, while the compressive strength was increased from 10.3 ± 3.3 MPa to 59.4 ± 20.3 MPa and the Young's modulus increased from 0.8 ± 0.3 GPa to 1.8 ± 0.3 GPa. The pore size and porosity are similar to that of cancellous bone, meanwhile the compressive strength is higher than that of cancellous bone, and the Young's modulus is between that of cancellous bone and cortical bone. Porosity, pore size and mechanical properties can be controlled by the parameters in such multiple coating processes. Therefore the porous T{i}6Al4V with the characteristics of cancellous bone is expected to be a promising biomaterial for biomedical applications.
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H. U. Cameron, R. M. Pilliar and I. Macnab, J Biomed. Mater. Res. 10 (1976) 295.
B. S. Chang, C. K. Lee, K. S. Hong, H. J. Youn, H. S. Ryu and S. S. Chung, Biomaterials 21 (2000) 1291.
A. J. Clemow, A. M. Weinstein, J. J. Klawitter, J. Koeneman and J. Anderson, J Biomed Mater Res. 15 (1981) 73.
J. D. Bobyn, R. M. Pilliar, H. U. Cameron, G. C. Weatherly and G. M. Kent, Clin Orthop. (1980) 291.
E. W. White, J. N. Weber, D. M. Roy, E. L. Owen, R. T. Chiroff and R. A. White, J. Biomed. Mater. Res. 9 (1975) 23.
J. E. Lemons and L. C. Lucas, J Arthroplasty. 1 (1986) 143.
R. D. Crowninshield, Instr Course Lect. 35 (1986) 144.
D. D. Moyle, J. J. Klawitter and S. F. Hulbert, J. Biomed. Mater. Res. 7 (1973) 363.
Marc Long and H. J. Rack, Biomaterials. 19(1998) 1621.
R. M. Pilliar, Intern. J. Powder Metallurgy. 34 (1998) 33.
B. Matin, S. Cornelia, H. P. Bronkremer and H. Baur, Advance Eng. Mater. 2 (2000) 196.
J. P. Li, S. H. Li, C. A. Van Blitterswijk and K. De Groot, J. Biomed. Mater. Res. 73A (2005) 223.
R. Brezny and D. J. Green, J. Am. Ceram. Soc. 72 (1989) 1145.
F. F. Lange and M. Metcalf, ibid. 68 (1985) 225.
J. P. Li, S. H. Li and K. De Groot, Key Eng. Mater. 218 (2001) 52.
J. P. Li, C. A. Van Blitterswijk and K. De Groot, J. Mat. Sci:Mat in Med. 15 (2004) 951.
S. H. Li, J. R. De Wijn, J. P. Li and P. Layrolle, Tissue Engin. 9 (2003) 535.
M. J. Grimm and J. L. Williams, J. Biomechanics 30 (1997) 743.
J. Y. Lin and Y. Zhang, Powder Metallurgy Technology. 18 (2000) 12.
L. J. Gibson and M. F. Ashby, in “Cellular Solids: Structure and Properties” (Cambridge University Press, Cambridge, 1997).
E. Cheal, M. Spector and W. Hayes, J. Orthop. Res. 10 (1992) 405.
P. Prendergast and D. Taylor, J. Biomed. Eng. 12 (1990) 379.
J. L. Lewis, M. J. Askew, R. L. Wixson, G. M. Kramer and R. R. Tarr, J Bone Joint Surg. 66-A (1984) 280.
W. F. Ho, C. P. Ju and J. H. Chern, Biomaterials 20 (1999) 2115.
Y. Okazaki, Y. Ito, A. Ito and T. Tateishi, Mater Trans.34 (1993) 1217.
T. Ahmed, M. Long, J. Silvestri, C. Ruiz and H. J. Rack, in the 8th World Titanium Conference. 1995, Birmingham, UK.
J. D. Bobyn, S. A. Hacking and S. P. Chan, in Scientific Exhibit, Proc of AAOS, Anaheim, CA (1999).
J. J. Krygier, J. D. Bobyn and R. A. Poggie, in Proc SIROT, Sydney, Australia (1999).
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Li, J.P., Li, S.H., Blitterswijk, C.A.V. et al. Cancellous bone from porous T{i}6Al4V by multiple coating technique. J Mater Sci: Mater Med 17, 179–185 (2006). https://doi.org/10.1007/s10856-006-6822-4
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DOI: https://doi.org/10.1007/s10856-006-6822-4