Membrane thickness design of implantable bio-MEMS sensors for the in-situ monitoring of blood flow

  • C. A. Steeves
  • Y. L. Young
  • Z. Liu
  • A. Bapat
  • K. Bhalerao
  • A. B. O. Soboyejo
  • W. O. Soboyejo


This paper presents some ideas for the membrane thickness design of of implantable bio-micro-electro-mechanical systems (bio-MEMS) for the in situ monitoring of blood flow. The objective is to develop a smart wireless sensing unit for non-invasive early stenosis detection in heart bypass grafts. The design includes considerations of nonlinear material models, multiscale blood flows, and appropriate analyical models for data interpretation, as well as preliminary studies of the pressure and flow sensing concepts. The paper also examines the use of surface coatings for the design on biocompatibility and non-adhesion of blood platelets and constituents. The implications of the results are discussed for in vivo deployment of such sensor systems.


Pressure Drop Atherosclerotic Plaque Arterial Wall Internal Pressure Pressure Sensor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media, LLC 2006

Authors and Affiliations

  • C. A. Steeves
    • 1
  • Y. L. Young
    • 2
  • Z. Liu
    • 2
  • A. Bapat
    • 3
  • K. Bhalerao
    • 4
  • A. B. O. Soboyejo
    • 4
  • W. O. Soboyejo
    • 5
  1. 1.Department of Mechanical and Aerospace EngineeringPrinceton UniversityPrinceton
  2. 2.Department of Civil and Environmental EngineeringPrinceton UniversityPrinceton
  3. 3.Department of Chemical EngineeringMcGill UniversityMontrealCanada
  4. 4.Department of Food, Agricultural and Biological EngineeringOhio State UniversityColumbus
  5. 5.Department of Mechanical and Aerospace EngineeringPrinceton UniversityPrinceton

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