Abstract
The effect of acetaminophen, a well known analgesic and fever-reducing medicine, on the calcium carbonate crystal growth was investigated under plethostatic conditions. The calcification rates measured was reduced by 9.1–63.2% in the presence of acetaminophen. Kinetic analysis according to a Langmuir-type adsorption isotherm lead to the calculation of an affinity constant K aff = 8.33 × 102 dm3 mol−1. The apparent order found from kinetic data was two suggesting a surface diffusion controlled spiral growth mechanism.
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C. S. SIKES and A. P. WHEEL ER, Chemtech (1988) 20
K. SIMKISS, Am. Zool. 24 (1984) 847
G. KPAMPITZ and G. GRASER, Angew. Chem. Int. Ed. Engl. 27 (1988) 1145
B. B. TOMAZIC, W. E. BROWN and F. J. SCHOEN, J. Biowed. Mater. Res. 28 (1994) 35
H. Sarles, Gastroenterology 66 (1974) 604
D. GLEESON, K. A. HOOD, G. M. MURPHY and R. H. DOWLING, Gastrenterology 102(5) (1992) 1707
D. I. HAY, S. K. SCHLUCKEBIER and E. C. MORENO, Calcif. Tissue Int. 39 (1986) 151
S. D. STRICHARTZ, M. Z. ABEDIN, M. S.ABDOU and J. J. ROSLYN, Am. J. Surgery 155 (1988) 131
M. C. FRINCU, R. E. SHARPE and J. A. SWIFT, Crystal Growth Des. 4 (2004) 223
D. C. DAHLIN and S. D. NELSON, J. Med. Chem. 25 (1982) 885
J. A. HINSON, Rev. Biochem. Toxicol. 2 (1980) 103
D. AMMER and D. J. GREEN-BLATT, Ann. Intern. Med. 87 (1977) 202
J. E. FAINBROTHER, Anal. Profiles Drug Subs. 3 (1974) 109
M. B. TOMSON and G. H. NANCOLLAS, Science 200 (1977) 1059
T. F. KAZMIERCZAK, M. B. TOMSON and G. H. NANCOLLAS, J. Phys. Chem. 86 (1982) 103
E. GIANNIMARAS and P. G. KOUTSOUKOS, J. Colloid Int. Sci. 116 (1987) 423
G.H. NANCOLLAS, Interactions in Electrolyte Solutions (Elsevier: Amsterdam 1966)
ASTM Card file No. 5–0586
F. MANOLI, S. KOUTSOPOULOS and E. DALAS, J. Crystal Growth 182 (1997) 116
E. DALAS and P. G. KOUTSOUKOS, Lngmuir 4 (1998) 907
F. MANOLI and E. DALAS, J. Crystal Growth 204 (1999) 369
N. L. PLUMMER T. M. L. WIGLEY and D. C. PARKHURST, Am. J. Sci. 278 (1978) 179
A. E. NIELSEN and J. M. TOFT, J. Crystal Growth 67 (1964) 278
A. E. NIELSEN, Pure Appl. Chem. 53 (1981) 2025
G. H. NANCOLLAS, Biomineralization, edited by S. Mann, J. Webb, R. J. P. Williams (VCH Weinheim, F. R. Germany, 1989) pp. 156–187
D. N. MISRA, Langmuir, 4 (1988) 953
P. MALKAJ and E. DALAS, J. Crystal Growth 242 (2002) 405
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Malkaj, P., Dalas, E. The effect of acetaminophen on the crystal growth of calcium carbonate. J Mater Sci: Mater Med 18, 871–875 (2007). https://doi.org/10.1007/s10856-006-0065-2
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DOI: https://doi.org/10.1007/s10856-006-0065-2