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In vitro properties of PLLA screws and novel bioabsorbable implant with elastic nucleus to replace intervertebral disc

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Abstract

The suitability of two different implant types for the replacement of the intervertebral disc was studied in vitro. Self-reinforced poly-L-lactide (SR-PLLA) screws Ø 4.5 mm were studied 24 weeks in vitro and cylindrical implants with elastic nucleus made of poly(L/D)lactide 96/4, poly(L/DL)lactide 70/30, Bioactive Glass n:o 13–93 and Polyactive® 1000PEOT70PBT30 were studied 15 weeks in vitro. The cylindrical implant mimics the size and shape of the intervertebral disc. During the in vitro, there were no changes in compression properties with either implant types. The screws had sufficient modulus for intervertebral ossification in the canine model and the cylindrical implant showed also sufficient mechanical properties. These results suggest that both implant types could be used in clinical testing.

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Authors and Affiliations

  1. Institute of Biomaterials, Tampere University of Technology, P.O. Box 589, FIN-33101, Tampere, Finland

    V. Ellä, M. Kellomäki & P. Törmälä

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  1. V. Ellä
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  2. M. Kellomäki
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  3. P. Törmälä
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Correspondence to V. Ellä.

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Ellä, V., Kellomäki, M. & Törmälä, P. In vitro properties of PLLA screws and novel bioabsorbable implant with elastic nucleus to replace intervertebral disc. J Mater Sci: Mater Med 16, 655–662 (2005). https://doi.org/10.1007/s10856-005-2537-1

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  • DOI: https://doi.org/10.1007/s10856-005-2537-1

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