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Mangifera indica leaf extract assisted biogenic silver nanoparticles potentiates photocatalytic activity and cytotoxicity

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Abstract

The present study portrays, a low-cost, environmentally benign, and green route synthesis of Mangifera indica leaf extract mediated silver nanoparticles (MI:AgNPs). MI:AgNPs were characterized using analytical techniques such as X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), UV–Visible spectroscopy, Transmission Electron Microscopy (TEM). The structural characterization revealed that MI:AgNPs exhibited face centered cubic crystallinity with space group \(Fm\overline{3 }m\) without any traces of impurities and secondary phases. FTIR spectra confirmed the presence of phytochemicals (such as alkaloids, polyphenols, flavonoids, etc.) present in leaf extract, which serves as reducing, stabilizing and capping agent. UV–Vis spectra showed a sharp absorption peak in the UV region belonging to leaf extract and a hump in the visible region (~ 404 nm) attributed to the formation of AgNPs. TEM micrograph showed pseudo-spherical particles with average diameter of 18.2 ± 0.12 nm. MI:AgNPs showed enhanced photocatalytic activity against Methylene Blue (MB) dye under UV radiation. Cytotoxic activity was carried out on cervical cancer cell line (HeLa) at different concentrations of MI:AgNPs, which displayed potent anti-cancerous potential and illustrated the efficacy of MI:AgNPs with a low IC50 value 83.85 ± 9.63 µg/mL. The low-cost synthesis and effective cytotoxic potential of MI:AgNPs can make them an attractive choice for biomedical application.

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Data availability

The datasets generated during the current study will be available from the corresponding author on reasonable request.

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Acknowledgements

Authors are thankful to the Director, Sophisticated Analytical Instrumentation Facility (SAIF),

Panjab University, Chandigarh, India, for providing characterization facilities.

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Authors and Affiliations

  1. Department of Metallurgical and Materials Engineering, Punjab Engineering College (Deemed to be University), Chandigarh, 160012, India

    Ranvir Singh Panwar

  2. Department of Zoology, Panjab University, Chandigarh, 160014, India

    Naveed Pervaiz & Ravinder Kumar

  3. Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, India

    Gulshan Dhillon

  4. Department of Physics, Chandigarh University, Gharuan, Mohali, 140413, India

    Sanjeev Kumar, Nupur Aggarwal & Naveen Kumar

  5. Department of Physics and Astronomical Sciences, Central University of Jammu, Jammu, 180001, India

    Navdeep Sharma

  6. Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland, WA, 99354, USA

    Shalini Tripathi

  7. Department of Forensic Science, University of Ladakh, Leh, 194101, India

    Aseem Vashisht

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  1. Ranvir Singh Panwar
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  2. Naveed Pervaiz
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  4. Sanjeev Kumar
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  8. Ravinder Kumar
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  10. Naveen Kumar
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Contributions

1. Conceptualization: GD; 2. Methodology: RK; 3. Dye degradation lab facility provider: AV; 4. Formal analysis and investigation: NA; 5. Writing (original draft): RSP; 6. Writing (review and editing): SK; 7. Cytotoxic activity experimentation: NP; 8. Co-supervision: NS; 9. Resources for physicochemical characterization: ST; 10. Supervision: Naveen Kumar.

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Correspondence to Naveen Kumar.

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Panwar, R.S., Pervaiz, N., Dhillon, G. et al. Mangifera indica leaf extract assisted biogenic silver nanoparticles potentiates photocatalytic activity and cytotoxicity. J Mater Sci: Mater Electron 33, 16538–16549 (2022). https://doi.org/10.1007/s10854-022-08546-6

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