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CeO2 nanoparticles based extended gate field effect transistor for enzyme free detection of glucose

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Abstract

Herein, we report CeO2 nanoparticles (CeO2 NPs) based extended gate field effect transistor for glucose detection with high sensitivity and selectivity. Glucose sensing electrode was prepared by coating CeO2 NPs on copper foil using polyvinylidene fluoride as binder. Henceforth, above coated electrode is called CeO2 NPs electrode. Response of CeO2 NPs electrode towards glucose was examined through change in drain current in the applied voltage range of 0 to 0.6 V. CeO2 NPs electrode displayed excellent response towards glucose detection and this electrode exhibited linear response with concentration ranging from 1.5 to 9 mM. Sensitivity of CeO2 NPs electrode was evaluated, and it was found to be 45.28 µA/g mM cm2. Selectivity of CeO2 NPs was carried out against ascorbic acid, fructose, and sucrose. It was found that this electrode displayed negligible interference towards fructose and sucrose, however minimal interference was noticed in presence of ascorbic acid.

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References

  1. S. Vigneshvar, C.C. Sudhakumari, B. Senthilkumaran, H. Prakash, Front. Bioeng. Biotechnol. 4, 1 (2016)

    Article  Google Scholar 

  2. F. Valentini, L.G. Fernàndez, E. Tamburri, G. Palleschi, Biosens. Bioelectron. 43, 75 (2013)

    Article  CAS  Google Scholar 

  3. P.J. Ko, R. Ishikawa, H. Sohn, A. Sandhu, J. Nanosci. Nanotechnol. 13, 2451 (2013)

    Article  CAS  Google Scholar 

  4. Y. Zhou, C.W. Chiu, H. Liang, Sensors (Switzerland) 12, 15036 (2012)

    Article  CAS  Google Scholar 

  5. X. Guo, Adv. Mater. 25, 10488 (2013)

    Google Scholar 

  6. B. Dinesh, K.S. Shalini Devi, U.M. Krishnan, ACS Appl. Bio Mater. 2, 1740 (2019)

    Article  CAS  Google Scholar 

  7. A.F. Quintero-Jaime, Á. Berenguer-Murcia, D. Cazorla-Amorós, E. Morallón, Front. Chem. 7, 1 (2019)

    Article  Google Scholar 

  8. N. Saravanan, P. Mayuri, A.S. Kumar, ACS Appl. Bio Mater. 1, 1758 (2018)

    Article  CAS  Google Scholar 

  9. R.B. Rakhi, K. Sethupathi, S. Ramaprabhu, J. Phys. Chem. B 113, 3190 (2009)

    Article  CAS  Google Scholar 

  10. S.-K. Kim, C. Jeon, G.-H. Lee, J. Koo, S.H. Cho, S. Han, M.-H. Shin, J.-Y. Sim, S.K. Hahn, ACS Appl. Mater. Interfaces 11, 37347 (2019)

    Article  CAS  Google Scholar 

  11. F. Shang, J.D. Glennon, J.H.T. Luong, J. Phys. Chem. C 112, 20258 (2008)

    Article  CAS  Google Scholar 

  12. J. Soto, T. Hughes, Y.S. Li, ACS Omega 4, 18312 (2019)

    Article  CAS  Google Scholar 

  13. Y. Liu, H. Teng, H. Hou, T. You, Biosens. Bioelectron. 24, 3329 (2009)

    Article  CAS  Google Scholar 

  14. N.I. Chandrasekaran, M. Matheswaran, ACS Omega 5, 23502 (2020)

    Article  CAS  Google Scholar 

  15. S. Vinoth, P. Mary Rajaitha, A. Venkadesh, K.S. Shalini Devi, Nanoscale Adv. 2, 4242 (2020)

    Article  CAS  Google Scholar 

  16. S. Vinoth, K.S.S. Devi, A. Pandikumar, Trends Anal. Chem. 140, 116274 (2021)

    Article  CAS  Google Scholar 

  17. Y. Sivalingam, R. Pudi, L. Lvova, G. Pomarico, F. Basoli, A. Catini, A. Legin, R. Paolesse, C. Di, Sens. Actuators B: Chem. 209, 613 (2015)

    Article  CAS  Google Scholar 

  18. J. Wang, D.F. Thomas, A. Chen, Anal. Chem. 80, 997 (2008)

    Article  CAS  Google Scholar 

  19. P. Shanmugam, K. Pushparaj, A. Sundaramurthy, Y. Sivalingam, J. Mol. Struct. 131831 (2021)

  20. S.A. Mock, S.E. Sharp, T.R. Stoner, M.J. Radetic, E.T. Zell, R. Wang, J. Colloid Interface Sci. 466, 261 (2016)

    Article  CAS  Google Scholar 

  21. G. Seong, M. Dejhosseini, T. Adschiri, Appl. Catal. A: Gen. 550, 284 (2018)

    Article  CAS  Google Scholar 

  22. C. Hua, X. Fang, Z. Yang, Y. Gao, Z. Wang, L. Chen, Electrochem. Commun. 25, 66 (2012)

    Article  CAS  Google Scholar 

  23. B. Wang, B. Zhu, S. Yun, W. Zhang, C. Xia, M. Afzal, Y. Cai, Y. Liu, Y. Wang, H. Wang, NPG Asia Mater. 11(1), 1–2 (2019)

    Article  Google Scholar 

  24. D. Basu, S. Basu, Int. J. Hydrog. Energy 37, 4678 (2011)

    Article  Google Scholar 

  25. A. Umar, T. Almas, A.A. Ibrahim, R. Kumar, M.S. Alassiri, J. Electroanal. Chem. 864, 1 (2020)

    Article  Google Scholar 

  26. D. Patil, N.Q. Dung, H. Jung, S.Y. Ahn, D.M. Jang, D. Kim, Biosens. Bioelectron. 31, 176 (2012)

    Article  CAS  Google Scholar 

  27. S.A. Pullano, C.D. Critello, I. Mahbub, N.T. Tasneem, S. Shamsir, S.K. Islam, M. Greco, A.S. Fiorillo, Sensors (Switzerland) 18, 4042 (2018)

    Article  Google Scholar 

  28. D. Parimi, V. Sundararajan, O. Sadak, S. Gunasekaran, S.S. Mohideen, A. Sundaramurthy, ACS Omega 4, 104 (2019)

    Article  CAS  Google Scholar 

  29. A. Aranda, E. Aylón, B. Solsona, R. Murillo, A.M. Mastral, D.R. Sellick, S. Agouram, T. García, S.H. Taylor, Chem. Commun. 48, 4704 (2012)

    Article  CAS  Google Scholar 

  30. Z. Zhang, Y. Wang, M. Wang, J. Lü, L. Li, Z. Zhang, M. Li, J. Jiang, F. Wang, Cuihua Xuebao/Chin. J. Catal. 36, 1623 (2015)

    Article  CAS  Google Scholar 

  31. S. Singh, T. Dosani, A.S. Karakoti, A. Kumar, S. Seal, W.T. Self, Biomaterials 32, 6745 (2011)

    Article  CAS  Google Scholar 

  32. K. Singh, B.S. Lou, J.L. Her, S.T. Pang, T.M. Pan, Sens. Actuators B Chem. 298, 126837 (2019)

    Article  CAS  Google Scholar 

  33. C.H. Kao, H. Chen, L.T. Kuo, J.C. Wang, Y.T. Chen, Y.C. Chu, C.Y. Chen, C.S. Lai, S.W. Chang, C.W. Chang, Sens. Actuators B Chem. 194, 419 (2014)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We thank the Department of Science and Technology (DST)—Science and Engineering Research Board (SERB), Government of India for financial support (ECR/2017/001218). We acknowledge SRMIST for characterization and lab facilities. Also, we are thankful to SRM institute of Science and Technology for providing the scholarship to carry out this research work.

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Authors and Affiliations

  1. Laboratory of Sensors, Energy and Electronic Devices (Lab SEED), Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India

    Punitha Shanmugam, Guru Prasad Kuppuswamy, Kishore Pushparaj & Yuvaraj Sivalingam

  2. H1 Energy Technologies, Pondicherry, 605005, India

    Balamurugan Arumugam

  3. Biomaterials Lab, Department of Chemical Engineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India

    Anandhakumar Sundaramurthy

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  1. Punitha Shanmugam
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  2. Guru Prasad Kuppuswamy
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  3. Kishore Pushparaj
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  4. Balamurugan Arumugam
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  5. Anandhakumar Sundaramurthy
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  6. Yuvaraj Sivalingam
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Correspondence to Anandhakumar Sundaramurthy or Yuvaraj Sivalingam.

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Shanmugam, P., Kuppuswamy, G.P., Pushparaj, K. et al. CeO2 nanoparticles based extended gate field effect transistor for enzyme free detection of glucose. J Mater Sci: Mater Electron 33, 9483–9489 (2022). https://doi.org/10.1007/s10854-021-07441-w

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  • DOI: https://doi.org/10.1007/s10854-021-07441-w

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