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Low-cost electrochemical sensor based on montmorillonite for antibiotic tetracycline hydrochloride detection

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Abstract

Tetracycline hydrochloride (TC(HCl)) has been extensively used as veterinary drugs and food additives in feed, but the abuse of TC(HCl) poses a great threat to the ecological environment and human health. In this paper, TC(HCl) in aqueous solution was successfully probed by an iron cation exchanged montmorillonite modified glassy carbon electrode (Fe-Mt/GCE) via a direct voltametric method. The electrochemical response sensitivity of Fe-Mt-150/GCE is 27.1 µA µM−1 cm−2. Compared with the traditional electrode, the Fe-Mt/GCE exhibits higher response current intensity in the rapid scanning process, which should be contributed to the larger surface area and more active sites of the modified electrode for the oxidation reaction of TC(HCl). Additionally, it is found that higher scanning corresponds to better signal, implying there are enough active sites in Fe-Mt/GCE for TC(HCl) detection. The machine learning method was further employed to explore the optimum parameters. The predicted data are highly consistent with the experimental data, which were verified by the testing phase in machine learning. The application of machine learning to describe and summarize the data may bring new ideas to the future researches. Montmorillonite could be potentially applied as an electrochemical sensor for antibiotic tetracycline hydrochloride detection due to its low cost and easy fabrication.

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Funding

The work was the financial support from the Innovation Science Foundation of Wuhan Institute of Technology (Grant No. CX2020152), Natural Science Foundation of Hubei Province (Grant No. 2020CFB279) and Scientific Research Program of Hubei Province Department of Education (Grant No. B2020052).

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Authors and Affiliations

  1. Hubei Key Laboratory of Plasma Chemical and Advanced Materials, Department of Materials Science and Engineering, Wuhan Institute of Technology, Wuhan, 430205, China

    Qiwen Guo, Zhe Chen, Geming Wang & Zhidong Lin

  2. Key Laboratory of Resource Chemistry and Eco-Environmental Protection of Qinghai-Tibet Plateau, Key Laboratory of Applied Physical Chemistry of Qinghai Province, School of Chemistry and Chemical Engineering, Qinghai Nationalities University, Xi’ning, 810007, China

    Xiaobo Yang

  3. School of Electrical and Information Engineering, Wuhan Institute of Technology, Wuhan, 430205, China

    Lei Yao

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  1. Qiwen Guo
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Correspondence to Zhe Chen.

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Guo, Q., Yang, X., Chen, Z. et al. Low-cost electrochemical sensor based on montmorillonite for antibiotic tetracycline hydrochloride detection. J Mater Sci: Mater Electron 33, 427–442 (2022). https://doi.org/10.1007/s10854-021-07316-0

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