Skip to main content
SpringerLink
Log in

High-performance non-enzymatic glucose-sensing electrode fabricated by α-nickel hydroxide-reduced graphene oxide nanocomposite on nickel foam substrate

  • Published:
Journal of Materials Science: Materials in Electronics Aims and scope Submit manuscript

Abstract

A non-enzymatic glucose-sensing material composed of α-nickel hydroxide nanosheets grown on reduced graphene oxide sheets (α-Ni(OH)2-rGO) is fabricated by a straightforward co-precipitation method. The morphology and composition of the α-Ni(OH)2-rGO are analyzed by field emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction, Raman spectroscopy, thermogravimetric analyzer, and X-ray photoelectron spectroscopy. The characterization results show that the content of Ni(OH)2 in the α-Ni(OH)2-rGO composites is about 82.77 wt%. The introduction of rGO can effectively prevent α-Ni(OH)2 from agglomeration. The thickness of the α-Ni(OH)2 sheets grown vertically on the rGO is less than 10 nm, and they are interwoven to form a porous network structure. Then, the α-Ni(OH)2-rGO/NiF (Nickel Foam)-sensing electrode is prepared with NiF as the substrate. The sensing mechanism and detection property of the α-Ni(OH)2-rGO/NiF-sensing electrode are researched through cyclic voltammetry (CV) and amperometry. The test results demonstrate that α-Ni(OH)2-rGO/NiF-sensing electrode has excellent glucose-sensing performance. Its linear detection range is as wide as 0.5–22.5 mM, and the sensitivity is as high as 95.5 μAmM−1 cm−2, which is obviously much better than previously studied glucose-sensing materials. Moreover, it is found that the prepared sensing electrode has excellent anti-interference and stability. After repeated measurements, the anodic peak current is only 6% lower than the initial current. More importantly, the sensing electrode also showed a good detection ability for actual samples, which fully confirms that α-Ni(OH)2-rGO/NiF-sensing electrode has good practical application potential.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. D. Zhou, X. Cao, Z. Wang, S. Hao, X. Hou, F. Qu, X. Sun, Fe3N-Co2N nanowires array: a non-noble-metal bifunctional catalyst electrode for high-performance glucose oxidation and H2O2 reduction toward non-enzymatic sensing application. Chem. Eur. J. 23, 5214–5218 (2017)

    Article  CAS  Google Scholar 

  2. Z.Z. Cui, H.Y. Yin, Q.L. Nie, D.Y. Qin, W.W. Wu, X.L. He, Hierarchical flower-like NiO hollow microspheres for non-enzymatic glucose sensors. J. Electroanal. Chem. 757, 51–57 (2015)

    Article  CAS  Google Scholar 

  3. P. Qu, Z. Gong, H. Cheng, W. Xiong, X. Wu, P. Pei, R. Zhao, Y. Zeng, Z. Zhu, Nanoflower-like CoS-decorated 3D porous carbon skeleton derived from rose for a high performance nonenzymatic glucose sensor. RSC Adv. 5, 106661–106667 (2015)

    Article  CAS  Google Scholar 

  4. Y. Zhang, H. Chen, C. Guan, Y. Wu, C. Yang, Z. Shen et al., Energy-saving synthesis of MOF-derived hierarchical and hollow Co(VO3)2-Co(OH)2composite leaf arrays for supercapacitor electrode materials. ACS Appl. Mater. Interfaces 10, 18440–18444 (2018)

    Article  CAS  Google Scholar 

  5. M. Dong, H.L. Hu, S.J. Ding, C.C. Wang, L. Li, A facile synthesis of CoMn2O4 nanosheets on reduced grapheme oxide for non-enzymatic glucose sensing. Nanotechnology 32, 055501 (2021)

    Article  CAS  Google Scholar 

  6. B.T. Dong, H. Zhou, J. Liang, L.S. Zhang, G.X. Gao, S.J. Ding, One-step synthesis of free-standing α-Ni(OH)2 nanosheets on reduced graphene oxide for high performance supercapacitors. Nanotechnology 25, 435403 (2014)

    Article  Google Scholar 

  7. M. Dong, H.L. Hu, S.J. Ding, C.C. Wang, L. Li, Fabrication of NiMn2O4 nanosheets on reduced graphene oxide for non-enzymatic detection of glucose. Mater. Technol. (2020). https://doi.org/10.1080/10667857.2020.1740861

    Article  Google Scholar 

  8. Y. Yang, H.J. Wang, L.L. Wang, Y.L. Ge, K. Kan, K.Y. Shi, J.H. Chen, A novel gas sensor based on porous α-Ni(OH)2 ultrathin nanosheet/reduced graphene oxide composites for room temperature detection of NO. New J. Chem. 40, 4678–4686 (2016)

    Article  CAS  Google Scholar 

  9. W.D. Fu, Y.H. Gong, M. Wang, Y.D. Yao et al., β-Ni(OH)2 nanosheets grown on graphene as advanced electrochemical pseudocapacitor materials with improved rate capability and cycle performance. Mater. Lett. 134, 107–110 (2014)

    Article  CAS  Google Scholar 

  10. I. Shakir, Z. Almutairi, S.S. Shar, A. Nafady, Nickel hydroxide nanoparticles and their hybrids with carbon nanotubes for electrochemical energy storage applications. Res. Phys. 17, 103117 (2020)

    Google Scholar 

  11. Y.D. Zhao, G.C. Gu, S.Q. You, R.H. Ji, H. Suo, C. Zhao, F.M. Liu, Preparation of Ni(OH)2 nanosheets on Ni foam via a direct precipitation method for a highly sensitive non-enzymatic glucose sensor. RSC Adv. 5, 53665–53670 (2015)

    Article  CAS  Google Scholar 

  12. Y. Zhang, F.G. Xu, Y.J. Sun, Y. Shi, Z.W. Wen, Z. Li, Assembly of Ni(OH)2 nanoplates on reduced graphene oxide: a two dimensional nanocomposite for enzyme-free glucose sensing. J. Mater. Chem. 21, 16949–16954 (2011)

    Article  CAS  Google Scholar 

  13. J.J. Chen, H.Y. Yin, J.L. Zhou, J.Y. Gong, L. Wang, Y.F. Zheng, Q.L. Nie, Non-enzymatic glucose sensor based on nickel nitride decorated nitrogen doped carbon spheres (Ni3N/NCS) via facile one pot nitridation process. J. Alloy. Compd. 797, 922–930 (2019)

    Article  CAS  Google Scholar 

  14. X.H. Liu, L. Yu, Influence of nanosized Ni(OH)2 addition on the electrochemical performance of nickel hydroxide electrode. J. Power Sources 128, 326–330 (2004)

    Article  CAS  Google Scholar 

  15. H. Chen, S.X. Zhou, L.M. Wu, Porous nickel hydroxide-manganese dioxide reduced graphene oxide ternary hybrid spheres as excellent supercapacitor electrode materials. ACS Appl. Mater. Interfaces 11, 8621–8630 (2014)

    Article  Google Scholar 

  16. X.W. Jian, Y.J. Zhu, W.H. Li, T.Q. Zhao, Crystal phase, structure stability and electrochemical performance of Co/Cu/Al substituted nano-sized alpha nickel hydroxide. Appl. Phys. A (2016). https://doi.org/10.1007/s00339-016-0443-7

    Article  Google Scholar 

  17. P. Lu, Y. Lei, S. Lu, Q. Wang, Q. Liu, Three-dimensional roselike α-Ni(OH)2 assembled from nanosheet building blocks for non-enzymatic glucose detection. Analytica Chim. Acta 23, 42–51 (2015)

    Article  Google Scholar 

  18. A. Gao, X.M. Zhang, X. Peng, H. Wu, L. Bai, W.H. Jin, G.S. Wu, R.Q. Hang, P.K. Chu, In situ synthesis of Ni(OH)2/TiO2 composite film on NiTi alloy for non-enzymatic glucose sensing. Sens. Actuators B. 232, 150–157 (2016)

    Article  CAS  Google Scholar 

  19. D. Ghosh, S. Giri, M. Mandal, C.K. Das, High performance supercapacitor electrode material based on vertically aligned PANI grown on reduced graphene oxide/Ni(OH)2 hybrid composite. RSC Adv. 4, 26094 (2014)

    Article  CAS  Google Scholar 

  20. J.P. Cheng, J. Zhang, F. Liu, Recent development of metal hydroxides as electrode material of electrochemical capacitors. RSC Adv. 4, 38893 (2014)

    Article  CAS  Google Scholar 

  21. S.S. Song, L.L. Zhang, H.Y. Shi, 3D nickel-cobalt double hydroxides nanosheets in situ grown on nitrogen-containing activated carbon for high-performance electrode materials. J. Alloy. Compd. 779, 59–66 (2019)

    Article  CAS  Google Scholar 

  22. L. Li, H.L. Hu, S.J. Ding, Facile synthesis of ultrathin and perpendicular NiMn2O4 nanosheets on reduced graphene oxide as advanced electrodes for supercapacitors. Inorg. Chem. Front. 5, 1714–1720 (2018)

    Article  CAS  Google Scholar 

  23. L. Li, H.L. Hu, S.J. Ding, X.Y. Yan, C.C. Wang, CoNi2S4 nanosheets on nitrogen-doped carbon foam as binder-free and flexible electrodes for high-performance asymmetric supercapacitors. Nanotechnology 30, 495404 (2019)

    Article  CAS  Google Scholar 

  24. Q. Wang, Y. Zhang, W.C. Ye, C.M. Wang, Ni(OH)2/MoS(x) nanocomposite electrodeposited on a flexible CNT/PI membrane as an electrochemical glucose sensor: the synergistic effect of Ni(OH)2 and MoS(x). J. Solid State Electrochem. 20, 133–142 (2015)

    Article  Google Scholar 

  25. G. Bharath, R. Madhu, S.M. Chen, V. Veeramani, A. Balamurugan, D. Mangalaraj, C. Viswanathan, N. Ponpandian, Enzymatic electrochemical glucose biosensors by mesoporous 1D hydroxyapatite-on-2D reduced graphene oxide. J. Mater. Chem. B 3, 1360–1370 (2015)

    Article  CAS  Google Scholar 

  26. M.A. Barik, R. Deka, J.C. Dutta, Carbon nanotube based dual-gated junctionless field effect transistor for acetylcholine detection. IEEE Sens. J. 16, 280–286 (2015)

    Article  Google Scholar 

  27. L. Zhang, Y.R. Ding, R.R. Li, C. Ye, G.Y. Zhao, Y. Wang, Ni-based metal-organic framework derived Ni@C nanosheets on a Ni foam substrate as a supersensitive non-enzymatic glucosesensor. J. Mater. Chem. B 5, 5549–5555 (2017)

    Article  CAS  Google Scholar 

  28. L. Qian, J. Mao, X. Tian, H. Yuan, D. Xiao, In situ synthesis of CuS nanotubes on Cu electrode for sensitive nonenzymatic glucose sensor. Sens. Actuators B. 176, 952–959 (2017)

    Article  Google Scholar 

  29. S. Malhotra, Y.J. Tang, P.K. Varshney, Non-enzymatic glucose sensor of high sensitivity fabricated with direct deposition of Au particles on polyvinylferrocene film modified Pt electrode. Chem. Pap. 73, 1987–1996 (2019)

    Article  CAS  Google Scholar 

  30. M. Zheng, L. Li, P. Gu, Z. Lin, H. Xue, H. Pang, A glassy carbon electrode modified with ordered nanoporous Co3O4 for non-enzymatic sensing of glucose. Microchim. ACTA 184, 943–949 (2017)

    Article  CAS  Google Scholar 

  31. D. Xu, C.L. Zhu, X. Meng, Z.X. Chen, Y. Li, D. Zhang, S.M. Zhu, Design and fabrication of Ag–CuO nanoparticles on reduced graphene oxide for nonenzymatic detection of glucose. Sens. Actuators B. 265, 435–442 (2018)

    Article  CAS  Google Scholar 

  32. X.F. Wu, C.C. Bao, Q.Q. Niu, W.B. Lu, A novel method to construct a 3D FeWO4 microsphere-array electrode as a non-enzymatic glucose sensor. Nanotechnology 30, 165501 (2019)

    Article  CAS  Google Scholar 

  33. X.J. Zhu, Y. Zhong, H.D. Zhai, Z. Yan, D.F. Li, Nanoflake nickel hydroxide and reduced graphene oxide composite as anode materials for high capacity lithium ion batteries. Electrochim. Acta 132, 364–369 (2014)

    Article  CAS  Google Scholar 

  34. X. Luo, M. Huang, D. He, M. Wang, Y. Zhang, P. Jiang, Porous NiCo2O4 nanoarray-integrated binder-free 3D open electrode offers a highly efficient sensing platform for enzymefree glucose detection. Analyst 143, 2546–2554 (2018)

    Article  CAS  Google Scholar 

  35. M. Balogun, Y. Zeng, W. Qiu, Y. Luo, A. Onasanya, T. Olaniyi, Y. Tong, Threedimensional nickel nitride (Ni3N) nanosheets: free standing and flexible electrodes for lithium ion batteries and supercapacitors. J. Mater. Chem. A 4, 9844–9849 (2016)

    Article  CAS  Google Scholar 

  36. Y. Mu, D. Jia, Y. He, Y. Miao, H.L. Wu, Nano nickel oxide modified non-enzymatic glucose sensors with enhanced sensitivity through an electrochemical process strategy at high potential. Biosens. Bioelectron. 26, 2948–2952 (2011)

    Article  CAS  Google Scholar 

  37. H. Gao, F. Xiao, C.B. Ching, H. Duan, One-step electrochemical synthesis of PtNi nanoparticle-graphene nanocomposites for nonenzymatic amperometric glucose detection. ACS Appl. Mater. Interfaces 3, 3049–3057 (2011)

    Article  CAS  Google Scholar 

  38. Y. Zhang, F. Xu, Y. Sun, Y. Shi, Z. Wen, Z. Li, Assembly of Ni(OH)2 nanoplates on reduced graphene oxide: a two dimensional nanocomposite for enzyme-free glucose sensing. J. Mater. Chem. 21, 16949–16954 (2011)

    Article  CAS  Google Scholar 

  39. L. Liu, Z. Wang, J. Yang, G. Liu, J. Li, L. Guo et al., NiCo2O4 nanoneedle-decorated electrospun carbon nanofibernanohybrids for sensitive non-enzymatic glucose sensors. Sens. Actuators B. 258, 920–928 (2018)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported in part by the National Natural Science Foundation of China under Grant No. 51777151, in part by the Shaanxi Provincial Key Technologies Research and Development Program under Grant No. 2016GY-001, and in part by the Fundamental Research Funds for the Central Universities under Grant No. xzy022019046.

Author information

Authors and Affiliations

  1. School of Electrical Engineering, State Key Laboratory of Electrical Insulation and Power Equipment, Xi′an Jiaotong University, Xi′an, 710049, China

    Min Dong, Hongli Hu & Changcheng Wang

  2. Department of Applied Chemistry, School of Science, MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, State Key Laboratory for Mechanical Behavior of Materials, Xi′an Jiaotong University, Xi′an, 710049, China

    Shujiang Ding

Authors
  1. Min Dong
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hongli Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shujiang Ding
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Changcheng Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hongli Hu.

Ethics declarations

Conflict of interest

There are no conflicts to declare.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Dong, M., Hu, H., Ding, S. et al. High-performance non-enzymatic glucose-sensing electrode fabricated by α-nickel hydroxide-reduced graphene oxide nanocomposite on nickel foam substrate. J Mater Sci: Mater Electron 32, 19327–19338 (2021). https://doi.org/10.1007/s10854-021-06451-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10854-021-06451-y

Search

Navigation