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From MOF membrane to 3D electrode: a new approach toward an electrochemical non-enzymatic glucose biosensor

  • Biomaterials
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Abstract

A three-dimensional (3D) nickel oxide (NiO) catalytic electrode was fabricated by annealing Ni2(L-asp)2bipy MOF membrane and was subsequently applied for electrochemical glucose sensor. This 3D self-supported MOF membrane precursor provided uniform and porous architecture, and it was used for fabricating 3D NiO electrode in the first time. The SEM and XRD data showed that the NiO was evenly distributed on Ni mesh and complete transformation from Ni2(L-asp)2bipy to NiO. This catalytic electrode, using a chronoamperometric approach, demonstrated linear range up to 400 μM with high sensitivity of 478.9 μA mM−1 cm−2 and low limit of detection of 4.34 μM. Uric acid, urea and ascorbic acid showed negligible interferences to the detection of glucose. The excellent performance of this electrode was attributed to the uniformly distributed NiO on the Ni substrate, direct electron transformation from Ni substrate to electrochemical active NiO and the porosity of such electrode design.

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Acknowledgements

The authors thank for the financial supports provided by National Natural Science Foundation of China (21501198).

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Authors and Affiliations

  1. College of Science, China University of Petroleum, Qingdao, 266580, China

    Yan Zhou, Sasa Wang & Zixi Kang

  2. College of Chemical Engineering, China University of Petroleum, Qingdao, 266580, China

    Jie Li & Jingtong Zhang

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  1. Yan Zhou
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  2. Jie Li
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  3. Sasa Wang
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  5. Zixi Kang
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Correspondence to Zixi Kang.

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Zhou, Y., Li, J., Wang, S. et al. From MOF membrane to 3D electrode: a new approach toward an electrochemical non-enzymatic glucose biosensor. J Mater Sci 52, 12089–12097 (2017). https://doi.org/10.1007/s10853-017-1349-2

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