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Recent developments in electrochemical sensors based on nanomaterials for determining glucose and its byproduct H2O2

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Abstract

The development in glucose and H2O2 electrochemical sensors has significantly progressed using some original nanomaterials, such as nanoparticles and nanowires in metal, metal oxide, or carbon nanomaterials. In this review, we discussed and analyzed the mechanism, performance, and characteristics of the enzyme/nonenzyme glucose and H2O2 electrochemical sensors based on some pure metal (Au, Pd, Ni, Pt, and Cu), metal oxide (ZnO, NiO, CuO x , TiO2, and Co3O4), and carbon (nanotubes and graphene) nanomaterials. Although the introduction of nanomaterials can effectively improve the sensitivity of enzyme glucose/H2O2 sensors by enhancing the activity of protein enzyme, the enzymes are sensitive to the biochemical environment. Meanwhile, the sensing performance of nonenzyme glucose/H2O2 sensors significantly depends on the morphology, uniformity, and distribution of nanomaterials.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (NSFC) under Grants (Numbers 61405032, 61403074, 61605031, 61425003); and Doctoral Scientific Research Startup Foundation of Liaoning Province under Grant (Number 201501144); and Fundamental Research Funds for the Central Universities under Grants (Numbers N150404022, N150401001). Jin Li acknowledges the financial support from the China Scholarship Council for his Research Scholarship No. 201606085023.

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Authors and Affiliations

  1. College of Information Science and Engineering, Northeastern University, No.11, Lane 3, Wenhua Road, Heping District, Shenyang, 110819, China

    Jin Li & Haifeng Hu

  2. Research School of Physics and Engineering, The Australian National University, Canberra, ACT, 0200, Australia

    Jin Li

  3. Key Laboratory of In-Fiber Integrated Optics, Ministry Education of China, Harbin Engineering University, Harbin, 150080, China

    Hanyang Li

  4. Key Laboratory of Photonic and Electric Bandgap Materials, Ministry of Education, School of Physics and Electronic Engineering, Harbin Normal University, Harbin, 150025, China

    Chengbao Yao

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  1. Jin Li
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Correspondence to Jin Li.

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Li, J., Hu, H., Li, H. et al. Recent developments in electrochemical sensors based on nanomaterials for determining glucose and its byproduct H2O2 . J Mater Sci 52, 10455–10469 (2017). https://doi.org/10.1007/s10853-017-1221-4

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