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Journal of Materials Science

, Volume 52, Issue 15, pp 8858–8870 | Cite as

Synthesis and dissolution behaviour of CaO/SrO-containing sol–gel-derived 58S glasses

  • Anthony L. B. MaçonEmail author
  • Sungho Lee
  • Gowsihan Poologasundarampillai
  • Toshihiro Kasuga
  • Julian R. JonesEmail author
In Honor of Larry Hench

Abstract

The effect of the substitution of strontium for calcium in the tertiary the SiO2–CaO–P2O5 sol–gel bioactive glass 58S (60SiO2·36CaO·4P2O5, mol%) on its structure and its chemical durability on soaking in simulated body fluids was investigated. 58S was selected as a starting composition, and substitution for calcium was carried out from 0 to 100% with an increment of 25%. A novel phosphate source of diethylphosphatoethyltriethoxysilane, which consists of Si and P connected with ethylene group, was used in this work. XRD and FTIR showed that the gels obtained following drying at 130 °C had a typical sol–gel structure, where a continuous amorphous silica gel network and surface bound mineral salts of Ca(NO3)2 and Sr(NO3)2. Once the gels were heat stabilised to decompose nitrates and incorporate the cations into the network, samples containing Sr formed a strontium silicate crystalline phase. With increasing levels of Sr in the composition, the overall crystallinity of the glass–ceramic increased, while, at the maximum substitution of 100% SrO, macroscopic phase separation was observed, characterised by needle-like crystals of strontium apatite (Sr5(PO4)3OH) and strontium silicate (Sr2SiO4) phases in addition to amorphous regions. Dissolution experiments in Tris-buffered solution showed Sr successfully released into the media even though it existed as a crystalline phase in the glass–ceramic. Further, the glass–ceramics induced nucleation and growth of carbonated hydroxyapatite (HA) on their surface suggesting potential bioactivity of the materials. At higher substitutions (75 and 100% SrO for CaO), HA nucleation was not found to occur this may have been due to low amount of phosphate released from the original glass–ceramic as a result of it being locked up in the strontium apatite phase.

Keywords

Strontium Simulated Body Fluid Bioactive Glass Heat Stabilisation Calcium Nitrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgements

The authors would like to thank Engineering and Physical Sciences Research Council (GB, EP/I020861/1) and Japan Society for the Promotion of Science (JSPS) international training program for funding this project. Raw data are available on request from alb.macon@nitech.ac.jp or julian.r.jones@imperial.ac.uk.

Supplementary material

10853_2017_869_MOESM1_ESM.docx (79 kb)
Supplementary material 1 (DOCX 79 kb)

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Anthony L. B. Maçon
    • 1
    • 2
    Email author
  • Sungho Lee
    • 3
    • 4
  • Gowsihan Poologasundarampillai
    • 5
  • Toshihiro Kasuga
    • 3
  • Julian R. Jones
    • 2
    Email author
  1. 1.Frontier Research Institute for Materials ScienceNagoya Institute of TechnologyNagoyaJapan
  2. 2.Department of MaterialsImperial College LondonLondonUK
  3. 3.Division of Advanced Ceramics, Graduate School of EngineeringNagoya Institute of TechnologyNagoyaJapan
  4. 4.Division of Materials and Manufacturing Science, Graduate School of EngineeringOsaka UniversitySuitaJapan
  5. 5.School of MaterialsThe University of ManchesterManchesterUK

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