Journal of Materials Science

, Volume 51, Issue 1, pp 513–553 | Cite as

Magnetic nanoparticles: material engineering and emerging applications in lithography and biomedicine

  • Yuping Bao
  • Tianlong Wen
  • Anna Cristina S. Samia
  • Amit Khandhar
  • Kannan M. KrishnanEmail author
50th Anniversary


We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several nontraditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body—an important and required practical consideration for any in vivo biomedical application, followed by a brief outlook of the field.


Magnetic Nanoparticles UHMWPE Iron Oxide Nanoparticles Magnetic Resonance Imaging Contrast Agent Nanoparticle Assembly 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Y. Bao was partially supported by NSF-DMR 0907204, DMR 114993, and Ralph Power Junior Faculty Enhancement Award. T. Wen acknowledges the financial support from the National Natural Science Foundation of China under contract # 51401046 and # 61131005. A. C. S. Samia is supported by an NSF-CAREER Grant (DMR-1253358). A. Khandhar and Kannan M. Krishnan acknowledge support from the NIH/NIBIB grant nos. 1R41EB013520-01 and 2R42EB013520-02A1. Kannan M. Krishnan was also supported under grant nos. NIH 1R01EB013689-01/NIBIB, NSF/DMR–0501421, and NSF/DMR #0203069.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Yuping Bao
    • 1
  • Tianlong Wen
    • 2
  • Anna Cristina S. Samia
    • 3
  • Amit Khandhar
    • 4
  • Kannan M. Krishnan
    • 5
    Email author
  1. 1.Chemical and Biological EngineeringThe University of AlabamaTuscaloosaUSA
  2. 2.State Key Laboratory of Electronic Thin Films and Integrated DevicesUniversity of Electronic Science and Technology of ChinaChengduChina
  3. 3.ChemistryCase Western Reserve UniversityClevelandUSA
  4. 4.Lodespin LabsSeattleUSA
  5. 5.Materials Science and EngineeringUniversity of WashingtonSeattleUSA

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