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Solid-phase steam-assisted synthesis of hydroxyapatite nanorods and nanoparticles

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Abstract

This article reports a novel and facile solid-based steam-assisted conversion method for the synthesis of hydroxyapatite (HAP, Ca10(PO4)6(OH)2) nanorods and nanoparticles. After steam treatment at 180 °C for 20 h, the wet solid of brushite (CaHPO4·2H2O), which was precipitated from reaction between calcium nitrate [Ca(NO3)2] and diammonium hydrogen phosphate [(NH4)2HPO4], was transformed to HAP nanorods with dimension of 100–300 nm in length and 56 ± 10 nm in diameter through a solid–gas reaction. By the same steam treatment, the dried brushite was converted to nanoparticles of HAP with small aspect ratio and particle size of 70 ± 18 nm. As compared with commercial HAP material, the nanostructured HAP materials exhibited superior sinterability in terms of density and hardness as well as excellent thermal stability. This simple, organic-free and cost-effective synthesis route with low reactant volume offers high potential for large-scale production of nanostructured HAP.

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Acknowledgement

This work was supported by the Science and Engineering Research Council of A*STAR (Agency for Science, Technology and Research), Singapore.

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Authors and Affiliations

  1. Institute of Chemical and Engineering Sciences, A*STAR (Agency for Science, Technology and Research), 1 Pesek Road, Jurong Island, 627833, Singapore

    Shou Cang Shen, Leonard Chia, Wai Kiong Ng, Yuan Cai Dong & Reginald B. H. Tan

  2. Department of Chemical and Biomolecular Engineering, The National University of Singapore, 4 Engineering Drive 4, Singapore, 117576, Singapore

    Reginald B. H. Tan

Authors
  1. Shou Cang Shen
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  2. Leonard Chia
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  3. Wai Kiong Ng
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  4. Yuan Cai Dong
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  5. Reginald B. H. Tan
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Corresponding authors

Correspondence to Shou Cang Shen or Reginald B. H. Tan.

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Shen, S.C., Chia, L., Ng, W.K. et al. Solid-phase steam-assisted synthesis of hydroxyapatite nanorods and nanoparticles. J Mater Sci 45, 6059–6067 (2010). https://doi.org/10.1007/s10853-010-4691-1

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  • DOI: https://doi.org/10.1007/s10853-010-4691-1

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