Abstract
Titanium and its alloys have been applied in orthopedics due to their biocompatibility, mechanical, and physical properties. Here we use decyl bis phosphonate (DBP) and collagen I to modify Ti–6Al–4V through layer-by-layer technique in order to improve its bioactivity. The abilities of bovine serum albumin (BSA) adsorption and biomimetic mineralization of different sample surfaces were studied. X-ray photoelectron spectroscopy (XPS) and water contact angle data showed that DBP and collagen I were assembled on substrates successfully. The absorbance of BSA solution acquired from ultraviolet spectrophotometer (UV) indicated that samples of Ti–6Al–4V/DBP/Collagen and Ti–6Al–4V/DBP/Collagen/DBP adsorbed BSA most, followed by Ti–6Al–4V/DBP and Ti–6Al–4V. Scanning electron microscope (SEM) photos and X-ray diffraction (XRD) data showed that sample of Ti–6Al–4V/DBP/Collagen had better bioactivity in inducing HA formation than other samples tested in this investigation.
Similar content being viewed by others
References
Gawalt ES, Avaltroni MJ, Danahy MP, Silverman BM, Hanson EL, Midwood KS, Schwarzbauer JE, Schwartz J (2003) Langmuir 19:200
Gawalt ES, Avaltroni MJ, Koch N, Schwartz J (2001) Langmuir 17:5736
Hansson HA, Albrektsson T, Branemark PI (1983) J Prosthet Dent 50:108
Albrektsson T, Jacobsson M (1987) J Prosthet Dent 57:597
Tryoen TP, Vautier D, Haikel Y, Voegel JC, Schaaf P (2002) J Biomed Mater Res 60:657
Richert L, Lavalle P, Payan E, Shu XZ, Prestwich GD (2004) Langmuir 20:448
Omelon SJ, Grynpas MD (2008) Chem Rev 108:4697
Chen YX, Liu WM, Ye CF, Yu LG, Qi SK (2001) Mater Res Bull 36:2605
Paszternák A, Stichleutner S, Felhősi I (2007) Electrochim Acta 53:337
Schuler M, Tosatti S, Gruner P, Garg R, Textor M (2003) Stability of self-assembled alkane phosphate/phosphonate monolayers on smooth titanium oxide. Swiss Federal Institute of Technology, Switzerland, p 1
Hanson EL, Schwartz J (2003) JACS 16074
Danahy MP, Avaltroni MJ, Midwood KS, Schwarzbauer JE, Schwartz J (2004) Langmuir 20:5333
Silverman BM, Wieghaus KA (2005) Langmuir 21:225
Zhang YY, Hu R, Chen F, Lin CJ (2005) J Biomed Eng 22:618
Chen F, Yu Y, Li SB, Lian GB (2006) China Surfactant Deterg Cosmet 36:331
Fan HH, Chen YP, Qiu F (2007) Fine Chem 24:961
Beck JS (1992) J Am Chem Soc 114:10834
Duan R, Zhang JJ, Du XQ, Yao XC, Konno K (2009) Food Chem 112:702
Gurpreet SB, Graeme KH, Harvey AG (2008) Matrix Biol 27:600
Jonasova L, Muller FA, Helebran A, Strnad J, Greil P (2004) Biomaterials 25:1187
Uchida M, Kim HM, Kokubo T, Fujibayashi S, Nakamura T (2003) J Biomed Mater Res 64:164
Frateur I, Lecoeur J, Zanna S, Olsson COA, Landolt D, Marcus P (2007) Electrochim acta 52:7660
Diana T, Hughes W, Graham E (1996) Biomaterials 17:859
Diana T, Hughes W, Rachel CH, Graham E (1995) Biomaterials 16:697
Tang K, Yan J (2007) China Surfactant Deterg Cosmet 37:410
Liu Q, Ding J, Mante FK, Wunder SL, Baran GR (2002) Biomaterials 23:3103
Pimanpang S, Wang PI, Senkevich JJ, Wang GC, Lu TM (2006) Colloid Surf A 278:53
Chang MC, Tanaka J (2002) Biomaterials 23:4811
Liu GB, Guo L, Feng Q, Liu YJ, Wang WL, Liao KJ (2002) Optoelectron Technol 22:144
Wei JH, Feng XH, Zhang JR (2008) Chin J Conserv Dent 18:396
Wassell DTH, Hall RC, Embery G (1995) Biomaterials 16:697
Dewez JL, Berger V, Schneider YJ, Rouxhet PG (1997) J Colloid Interf Sci 191:1
Michiardi A, Aparicio C, Ratner BD, Planell JA, Gil J (2007) Biomaterials 28:586
Janocha B, Hegemann D, Oehr C, Brunner H, Rupp F, Gerstorfer JG (2001) Surf Coat Technol 142–114:1051
Eustathopolos N, Nicholas MG, Drevet B (1999) Wettability at high temperatures. Pergamon Press, Oxford
Weeraphat PO, Siwaporn M, Tang IM (2008) Mater Chem Phys 112:453
Rogers KD, Etok SE (2004) J Mater Sci 39:5747. doi:10.1023/B:JMSC.0000040085.43633.8a
Zhang HY (2002) Biochemical tutorial. Sichuan University Press, Chengdu
Luong LH, Hong SI, Patel RJ, Outslay ME, Kohn DH (2006) Biomaterials 27:1175
Masami T, Takehisa M (1997) J Biomed Mater Res 34:305
Acknowledgements
This study was jointly supported by the Chinese NSFC (50871093), FANEDD (200554), and National Key Project of Scientific and Technical Supporting Programs funded by MSTC (2006BAI16B01). The authors gratefully acknowledge Dr. Yuancong Zhao for kindly providing guidance in DBP synthesis.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Ni, Y.X., Feng, B., Wang, J. et al. Decyl bis phosphonate–protein surface modification of Ti–6Al–4V via a layer-by-layer technique. J Mater Sci 44, 4031–4039 (2009). https://doi.org/10.1007/s10853-009-3562-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10853-009-3562-0