Composites of calcinated bovine bone-derived hydroxyapatite (BHA), doped with 2.5, 5, and 10 wt.% ZnO were produced by sintering. Scanning electron microscopy (SEM) and X-ray diffraction analysis together with measurements of density, compressive strength, and Vickers microhardness were carried out in the sintered samples. The experimental results showed that the best mechanical properties were achieved in the samples with 5% addition of ZnO. The highest value of compression strength was achieved after sintering at 1200 °C (72 MPa) and of microhardness at 1300 °C (548 HV). Prolong heat treatment at 1300 °C results in vulnerable BHA–ZnO composites to over-firing effect.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Oktar FN (2006) Mater Lett 60:2207
Oktar FN, Yetmez M, Agathopoulos S, Lopez Goerne TM, Goller G, Peker I, Ferreira JMF (2006) J Mater Sci Mater Med 17:1161
Goller G, Oktar FN (2002) Mater Lett 56:142
Oktar FN (2007) Ceram Int 33:1309
Kurkcu M, Benlidayi ME, Ozsoy S, Ozyegin LS, Oktar FN, Kurtoglu C (2008) J Mater Sci Mater Med 19:59
Erkmen EZ, Genc Y, Oktar FN (2007) J Am Ceram Soc 90:2285
Goller G, Oktar FN, Ozyegin LS, Kayali ES, Demirkesen E (2004) Mater Lett 58:2599
http://www.oie.int/eng/info/en_statesb.htm. Bovine spongiform encephalopathy (updated: 01/08/2006)
Mad cow disaese\BSE and vCJD Instant Expert - life - 04 September 2006 - Print - New Scientist.htm
http://www.oie.int/eng/info/en_esbmonde.htm. Last update: 27 July 2007 (fr)
http://www.oie.int/eng/info/en_esbcarte.htm. Geographical Distribution of Countries that reported BSE Confirmed Cases since 1989. Last update: 04 January 2007
http://www.europa.eu.int/comm/food/fs/sc/ssc/outcome_en.html. Final Report on the assessment of the Geographical BSE-risk of Turkey 27 June 2002
Opinion of the Scientific Steering Committee on the Geographical Risk Of Bovine Spongiform Encephalopathy (GBR) in Turkey Adopted by the SSC on 27 June 2002
Oktar FN, Kesenci K, Piskin E (1999) Artif Cell Blood Substit Immobil Biotechnol 27:367
Goller G, Oktar FN, Agathopoulos S, Tulyaganov DU, Ferreira JMF, Kayali ES, Peker I (2006) J Sol-Gel Sci Technol 37:111
Ozyegin LS, Oktar FN, Goller G, Kayali ES, Yazici T (2004) Mater Lett 58:2605
Carvalho AL, Faria PEP, Grisi MFM, Souza SLS, Taba MJ Jr, Palioto DB, Novaes AB Jr, Fraga AF, Ozyegin LS, Oktar FN, Salata LA (2007) J Oral Implantol 33:267
Oktar FN, Goller G (2002) Ceram Int 28:617
Bandyopadhyay A, Withey EA, Moore J, Bose S (2007) Mater Sci Eng C 27:14
Bertenshaw BW, Combe EC (1972) J Dent 1:65
Otsuka M, Marunaka S, Matsuda Y, Ito A, Layrolle P, Naito H, Ichinose N (2000) J Biomed Mater Res 52:819
Otsuka M, Ohshita Y, Marunaka S, Matsuda Y, Ito A, Ichinose N, Otsuka K, William I, Higuchi WI (2004) J Biomed Mater Res Part A 69A:552
British Standard for compression tests (No: 7253), BS EN. ISO 7253:2001, Test methods. Determination of modulus of elasticity in compression. www.bsiglobal.com/upload/Standards%20&%20Publications/Membership/UpdateStandards/October06.pdf
Goren S, Gokbayrak H, Altintas S (2004) Key Eng Mater 264–268:1949
Gokbayrak H (1996) Production of hydroxyapatite ceramics. M.Sc. Thesis, Bogazici University, Istanbul
Oktar FN, Aydin H, Goller G, Agathopoulos S, Rocha G, Sennaroglu B, Kayali S (2006) Key Eng Mater 309–311:45
Kamitakahara M, Ohtsuki C, Inada H, Tanihara M, Miyazaki T (2006) Acta Biomater 2:467
Du RL, Chang J, Ni SY, Zhai WY, Wang JY (2006) J Biomater Appl 20:341
Miaoa S, Wenga W, Chengb K, Dua P, Shena G, Hana G, Zhang S (2005) Surf Coat Technol 198:223
Wang Z, Xue D, Chen X, Lu B, Ratajczak H (2005) J Non-Cryst Solids 351:1675
Balamurugan A, Balossier G, Kannan S, Michel J, Rebelo AHS, Ferreira JMF (2007) Acta Biomater 3:255
Ito M (1991) Biomaterials 12:41
Vélez D, Arita IH, García-Garduño MV, Castaño VM (1994) Mater Lett 19:309
This study was carried out with the financial support of the Turkish Republic Government Planning Organization in the framework of the Project “Manufacturing and Characterization of Electro-Conductive Bioceramics” with project number 2003 K120810. The authors also acknowledge the technical support of assistant O. Meydanoglu, associate professor G. Goller, professor E.S. Kayali from Metallurgical and Materials Engineering Department of Istanbul Technical University, and L.S. Ozyegin from Dental Technical School of Health Related Professions, Istanbul, Turkey, for BHA production. The work of S. Agathopoulos in this paper has been in the framework of the Project ENTER 04EP26, co-financed by E.U.-European Social Fund (75%) and the Greek Ministry of Development-GSRT (25%). O. Gunduz also acknowledges the support of Prof. M. Edirisinghe from University College London where he is spending a sabbatical year.
About this article
Cite this article
Gunduz, O., Erkan, E.M., Daglilar, S. et al. Composites of bovine hydroxyapatite (BHA) and ZnO. J Mater Sci 43, 2536–2540 (2008). https://doi.org/10.1007/s10853-008-2497-1
- Compressive Strength
- Vickers Microhardness
- Secondary Porosity
- Bovine Bone