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Antibacterial activity of copper monodispersed nanoparticles into sepiolite


Copper monodispersed nanoparticles (2–5 nm) embedded into submicron particles of sepiolite (Mg8Si12O30(OH)4(H2O)4·8H2O), suitable to be used for biological applications have been obtained after a specific treatment and subsequent reduction process. Cu/Sepiolite particles have revealed as a strong bactericide (similar to Triclosan) so that they were able to decrease the starting microorganism concentrations of Staphylococcus aureus or Escherichia coli by 99.9%.

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The Spanish Ministry of Education and Science has supported this research under projects MAT2003-04199-C02 and PTR1995-0832-OP. We thank to Dr. Inmaculada Angulo-Varona (Gaiker Foundation, Spain) for her assistance in the antibacterial test. A.E.C. thanks financial support of the I3P grant by CSIC and European Social Fund (ESF).

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Correspondence to José S. Moya.

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Esteban-Cubillo, A., Pecharromán, C., Aguilar, E. et al. Antibacterial activity of copper monodispersed nanoparticles into sepiolite. J Mater Sci 41, 5208–5212 (2006).

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  • Inductively Couple Plasma Atomic Emission Spectrometry
  • Copper Concentration
  • Sepiolite
  • Triclosan
  • Copper Nanoparticles