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β-Cyclodextrin conjugated magnetic nanoparticles as a novel magnetic microvessel and phase transfer catalyst: synthesis and applications in nucleophilic substitution reaction of benzyl halides

Journal of Inclusion Phenomena and Macrocyclic Chemistry volume 76, pages 363–368 (2013)Cite this article

Abstract

This paper presents a feasible protocol for the preparation of β-cyclodextrin conjugated Fe3O4 magnetic nanoparticles as an efficient microvessel and host system for nucleophilic substitution reaction of benzyl halides in water. No evidence for the formation of by-product for example isothiocyanate or benzyl alcohol was observed and the products were obtained in pure form without further purification. The characteristics results of FT-IR, XRD, TGA and SEM shows that β-CD is grafted onto Fe3O4 nanoparticles. The nanomagnetic catalyst could be readily separated from solution via application of an external magnet, allowing straightforward recovery and reuse.

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Acknowledgments

We are grateful to the Research Council of Shahid Chamran University for financial support.

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Authors and Affiliations

  1. Chemistry Department, College of Science, Shahid Chamran University, 61357-4-3169, Ahvaz, Iran

    Ali Reza Kiasat & Simin Nazari

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  1. Ali Reza Kiasat
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  2. Simin Nazari
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Correspondence to Ali Reza Kiasat.

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Kiasat, A.R., Nazari, S. β-Cyclodextrin conjugated magnetic nanoparticles as a novel magnetic microvessel and phase transfer catalyst: synthesis and applications in nucleophilic substitution reaction of benzyl halides. J Incl Phenom Macrocycl Chem 76, 363–368 (2013). https://doi.org/10.1007/s10847-012-0207-8

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  • DOI: https://doi.org/10.1007/s10847-012-0207-8

Keywords

  • Magnetic nanoparticles
  • β-Cyclodextrin
  • Nucleophilic substitution
  • Benzyl thiocyanate
  • Benzyl azide