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Naphthyridine amide–urea conjugate: a case toward selective fluorometric sensing of N-acetyl proline carboxylate

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Abstract

A simple neutral naphthyridine-based chemosensor 1, which selectively recognizes the tetrabutylammonium salt of N-acetyl-l-proline over the other N-acetyl-l-amino acid salts studied in CHCl3 containing 0.1% DMSO, has been designed and synthesized. Moreover, the complexation-induced change in emission characteristics of 1 distinguishes the amino acid salts examined from their conjugate acids. Interaction studies were performed by UV–vis, fluorescence and NMR spectroscopic methods.

Graphical Abstract

A simple neutral naphthyridine –based chemosensor 1, which selectively recognizes the tetrabutylammonium salt of N-acetyl-l-proline in CHCl3 containing 0.1% DMSO, has been designed and synthesized. The complexation-induced change in emission characteristics of 1 distinguishes the amino acid salts from their conjugate acids.

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Acknowledgments

We thank CSIR, New Delhi, India for financial support. T.S thanks CSIR, New Delhi, India for providing fellowship. We also thank the reviewer for constructive criticism.

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  1. Department of Chemistry, University of Kalyani, Kalyani, Nadia, 741235, India

    Kumaresh Ghosh & Tanmay Sarkar

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  1. Kumaresh Ghosh
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  2. Tanmay Sarkar
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Correspondence to Kumaresh Ghosh.

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Ghosh, K., Sarkar, T. Naphthyridine amide–urea conjugate: a case toward selective fluorometric sensing of N-acetyl proline carboxylate. J Incl Phenom Macrocycl Chem 71, 243–248 (2011). https://doi.org/10.1007/s10847-011-9929-2

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  • DOI: https://doi.org/10.1007/s10847-011-9929-2

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