Abstract
A new type of fluorescent chemosensor, based on modified cyclodextrins bearing the fluorophore unit NBD-amine, was prepared. One of these new chemosensors, NC0γCD is very sensitive to bile acids, but is not sensitive to other guests (e.g. adamantane and borneol derivatives). The response of the new type of chemosensor to a guest was an increase in the fluorescence intensity and the sensitivity parameter (ΔI/I 0 ) dose not correlate to the binding affinity of NC0γCD.
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Acknowledgments
This article is dedicated to the honor and memory of Professor Akihiko Ueno, who passed away on March 23, 2003. We are grateful to Nihon Shokuhin Kako Co., Ltd. for the generous supply of cyclodextrins. This work was supported by a Grant-in-Aid for Science Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
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Ikeda, H., Murayama, T. & Ueno, A. Bile Acids-Selective Chemosensors Based on NBD-amine-Modified Cyclodextrins. J Incl Phenom Macrocycl Chem 56, 101–105 (2006). https://doi.org/10.1007/s10847-006-9069-2
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DOI: https://doi.org/10.1007/s10847-006-9069-2