abstract
The supramolecular chemistry of cucurbituril, a synthetic receptor, is fascinating because of the remarkable guest binding behavior of the host. Although cucurbituril is potentially as useful as crown ethers, cyclodextrins, and calixarenes in many applications, its chemistry has not been developed much until recently because of several shortcomings. Recently we synthesized cucurbituril homologues and derivatives. These new members of the cucurbituril family have expanded the scope further, and interest in them has grown enormously. The diversity in guest binding behavior has led to many interesting studies such as redox control of guest binding, stabilization of charge-transfer complexes inside the host cavity, encapsulation of drug molecules, formation of redox-controllable vesicles, and so on. The cucurbituril homologues and derivatives thus provide new opportunities in many areas of supramolecular chemistry including recognition, catalysis, separation, transport, and many others.
Similar content being viewed by others
References
R Behrend E Meyer F Rusche (1905) Liebigs Ann Chem 339 1
WA Freeman WL Mock N-Y Shih (1981) J Am Chem Soc 103 7367
WL Mock (1996) Cucurbituril FV Vögtle (Eds) Comprehensive Supramolecular Chemistry Pergamon Press Oxford Vol 2 477–493
(a) Y.-M. Jeon, D. Whang, J. Kim, and K. Kim: Chem. Lett. 503 (1996); (b) J.W. Lee, S.W. Choi, Y.H. Ko, S.-Y. Kim, and K. Kim: Bull. Korean Chem. Soc. 23, 1347 (2002)
(a) D. Whang, Y.-M. Jeon, J. Heo, and K. Kim: J. Am. Chem. Soc. 118, 11333 (1996); (b) D. Whang and K. Kim: J. Am. Chem. Soc. 119, 451 (1997); (c) E. Lee, J. Heo, and K. Kim: Angew. Chem. Int. Ed.39, 2699 (2000); (d) K.-M. Park, D. Whang, E. Lee, J. Heo, and K. Kim: Chem. Eur.J. 8, 498 (2002); (e) Y. Tan, S.W. Choi, J.W. Lee, Y.H. Ko, and K. Kim: Macromolecules 35, 7161 (2002); (f) S.W. Choi, J.W. Lee, Y.H. Ko, and K. Kim: Macromolecules 35, 3526 (2002); (g) K.-M. Park, S.-G. Roh, E. Lee, J. Kim, H.-J. Kim, J.W. Lee, and K. Kim: Supramol. Chem. 14, 153 (2002)
(a) D. Whang, K.-M. Park, J. Heo, P. Ashton, and K. Kim: J. Am. Chem. Soc.120, 4899 (1998); (b) S.-G. Roh, K.-M. Park, S. Sakamoto, K. Tamaguchi, and K. Kim: Angew. Chem. Int. Ed. 38, 637 (1999); (c) K.-M. Park, S.-Y. Kim, J. Heo, D. Whang, S.␣Sakamoto, K. Yamaguchi, and K. Kim: J. Am. Chem. Soc. 124, 2140 (2002)
JW Lee YH Ko S-H Park K Yamaguchi K Kim (2001) Angew Chem Int Ed 40 746
(a) S.I. Jun, J.W. Lee, S. Sakamoto, K. Yamaguchi, and K. Kim: Tetrahedron Lett. 41, 471 (2000); (b) J.W. Lee, K.P. Kim, and K. Kim: Chem. Commun. 1042 (2001)
H Isobe N Tomita JW Lee Kim H-J K Kim E Nakamura (2000) Angew Chem Int Ed 39 4257
Y-b Lim T Kim JW Lee S-M Kim H-J Kim K Kim J-S Park (2002) Bioconjugate Chem 13 1181
(a) K. Kim: Chem. Soc. Rev. 31, 96 (2002); (b) J.W. Lee and K.␣Kim: Top. Curr. Chem. 228, 111 (2003)
JW Lee S Samal N Selvapalam H-J Kim K Kim (2003) Acc Chem Res 36 621
WL Mock TA Irra JP Wepsiec M Adhya (1989) J Org Chem 54 5302
S Karcher A Kornmüller M Jekel (2001) Water Res 35 3309
J Kim I-S Jung S-Y Kim E Lee J-K Kang S Sakamoto K Yamaguchi K Kim (2000) J Am Chem Soc 122 540
H-J Kim WS Jeon YH Ko K Kim (2002) Proc Natl Acad Sci USA 99 5007
W Ong M Gómez-Kaifer AE Kaifer (2002) Org Lett 4 1791
A Mirzoian AE Kaifer (1997) Chem Eur J 3 1052
Jeon WS, Kim H-J, Lee C, Kim K (2002) Chem Commun 1828
H-J Kim J Heo WS Jeon E Lee J Kim S Sakamoto K Yamaguchi K Kim (2001) Angew Chem Int Ed 40 1526
YJ Jeon PK Bharadwaj SW Choi JW Lee K Kim (2002) Angew Chem Int Ed 41 4474
S-Y Kim I-S Jung E Lee J Kim S Sakamoto K Yamaguchi K Kim (2001) Angew Chem Int Ed 40 2119
Jon SY, Ko YH, Park S-H, Kim H-J, Kim K (2001) Chem Commun 1938
Choi SW, Park SH, Ziganshina AY, Ko YH, Lee JW, Kim K (2003) Chem Commun 2176
A Flinn GC Hough JF Stoddart DJ Williams (1992) Angew Chem Int Ed Engl 31 1475
XX Zhang KE Krakowiak G Xue JS Bradshaw RM Izatt (2000) Ind Eng Chem Res 39 3516
Y Miyahara K Abe T Inazu (2002) Angew Chem Int Ed 41 3020
J Zhao H-J Kim J Oh S-Y Kim JW Lee S Sakamoto K Yamaguchi K Kim (2001) Angew Chem Int Ed 40 4233
H Isobe S Sato E Nakamura (2002) Org Lett 4 1287
SY Jon N Selvapalam DH Oh J-K Kang S-Y Kim YJ Jeon JW Lee K Kim (2003) J Am Chem Soc 125 10186
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kim, K., Selvapalam, N. & Oh, D.H. Cucurbiturils–a New Family of Host Molecules. J Incl Phenom Macrocycl Chem 50, 31–36 (2004). https://doi.org/10.1007/s10847-003-8835-7
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10847-003-8835-7