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Pulsed field electroporation for pulmonary vein isolation—continued innovation to improve our atrial fibrillation armamentarium

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References

  1. Maor E, et al. Pulsed electric fields for cardiac ablation and beyond: a state-of-the-art review. Heart Rhythm. 2019;16(7):1112–20.

    Article  PubMed  Google Scholar 

  2. Sugrue A, et al. Irreversible electroporation for catheter-based cardiac ablation: a systematic review of the preclinical experience. J Interv Card Electrophysiol. 2019;55(3):251–65.

    Article  PubMed  Google Scholar 

  3. Reddy VY, et al. Pulsed field ablation of paroxysmal atrial fibrillation: 1-year outcomes of IMPULSE, PEFCAT, and PEFCAT II. JACC Clin Electrophysiol. 2021;7(5):614–27.

    Article  PubMed  Google Scholar 

  4. De Potter T, et al. Acute safety and performance outcomes from the inspIRE trial using a novel pulsed field ablation system for the treatment of paroxysmal atrial fibrillation. Eur Heart J. 2021;42:380.

  5. Verma A, et al. First-in-human experience and acute procedural outcomes using a novel pulsed field ablation system: the PULSED AF Pilot Trial. Circ Arrhythm Electrophysiol. 2022;15(1): e010168.

    Article  CAS  PubMed  Google Scholar 

  6. Füting A, et al. CA-536–04 Six-month follow-up of first real-world experience with pulmonary vein isolation using pulsed field ablation for paroxysmal atrial fibrillation. Heart Rhythm. 2022;19(5 Supplement):S92–3.

    Article  Google Scholar 

  7. Reddy VY, et al. Coronary arterial spasm during pulsed field ablation to treat atrial fibrillation. Circulation. 0(0):10.1161/CIRCULATIONAHA.122.061497.

  8. Zyl MV, et al. Reversible atrioventricular conduction impairment following bipolar nanosecond electroporation of the interventricular septum. JACC: Clin Electrophysiol. 2021;7(2):255–7.

    PubMed  Google Scholar 

  9. Yavin HD, et al. A lattice tip catheter for single-shot pulmonary vein isolation with pulsed field ablation. J Interv Card Electrophysiol. 2022. https://doi.org/10.1007/s10840-022-01414-7.

  10. Reddy VY, et al. Lattice-tip focal ablation catheter that toggles between radiofrequency and pulsed field energy to treat atrial fibrillation: a first-in-human trial. Circ Arrhythm Electrophysiol. 2020;13(6):e008718.

    Article  CAS  PubMed  Google Scholar 

  11. Yavin H, et al. Pulsed field ablation using a lattice electrode for focal energy delivery. Circ: Arrhythmia Electrophysiol. 2020;13(6):e008580.

    CAS  Google Scholar 

  12. DeSimone CV, et al. Novel balloon catheter device with pacing, ablating, electroporation, and drug-eluting capabilities for atrial fibrillation treatment–preliminary efficacy and safety studies in a canine model. Transl Res. 2014;164(6):508–14.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Kapa S, DeSimone CV, Asirvatham SJ. Innervation of the heart: an invisible grid within a black box. Trends Cardiovasc Med. 2016;26(3):245–57.

    Article  PubMed  Google Scholar 

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Correspondence to Christopher V. DeSimone.

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Dr. DeSimone reports intellectual property filed related to the use of electroporation for atrial fibrillation.

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Ward, R.C., DeSimone, C.V. Pulsed field electroporation for pulmonary vein isolation—continued innovation to improve our atrial fibrillation armamentarium. J Interv Card Electrophysiol 66, 1541–1543 (2023). https://doi.org/10.1007/s10840-022-01418-3

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