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Left atrial appendage occlusion: does it get the seal of approval?

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References

  1. Korsholm K, Kramer A, Andersen A, Saw J, Nørgaard BL, Jensen JM, Nielsen-Kudsk JE. Left atrial appendage sealing performance of the Amplatzer Amulet and Watchman FLX device. J Interv Card Electrophysiol. 2022. https://doi.org/10.1007/s10840-022-01336-4

  2. Kar S, Doshi SK, Sadhu A, Horton R, Osorio J, Ellis C, Stone J Jr, Shah M, Dukkipati SR, Adler S, Nair DG, Kim J, Wazni O, Price MJ, Asch FM, Holmes DR Jr, Shipley RD, Gordon NT, Allocco DJ, Reddy VY; PINNACLE FLX Investigators. Primary outcome evaluation of a next-generation left atrial appendage closure device: results from the PINNACLE FLX Trial. Circulation. 2021;143(18):1754–1762. https://doi.org/10.1161/CIRCULATIONAHA.120.050117.

  3. Reddy VY, Sievert H, Halperin J, Doshi SK, Buchbinder M, Neuzil P, Huber K, Whisenant B, Kar S, Swarup V, Gordon N, Holmes D; PROTECT AF Steering Committee and Investigators. Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation: a randomized clinical trial. JAMA. 2014;312(19):1988–98. https://doi.org/10.1001/jama.2014.15192.

  4. Holmes DR Jr, Kar S, Price MJ, Whisenant B, Sievert H, Doshi SK, Huber K, Reddy VY. Prospective randomized evaluation of the Watchman left atrial appendage closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J Am Coll Cardiol. 2014;64(1):1–12. https://doi.org/10.1016/j.jacc.2014.04.029 (Erratum in: J Am Coll Cardiol. 2014 Sep 16;64(11):1186).

    Article  PubMed  Google Scholar 

  5. Lakkireddy D, Thaler D, Ellis CR, Swarup V, Sondergaard L, Carroll J, Gold MR, Hermiller J, Diener HC, Schmidt B, MacDonald L, Mansour M, Maini B, O'Brien L, Windecker S. Amplatzer Amulet left atrial appendage occluder versus Watchman device for stroke prophylaxis (Amulet IDE): a randomized, controlled trial. Circulation. 2021;144(19):1543–1552. https://doi.org/10.1161/CIRCULATIONAHA.121.057063.

  6. Nielsen-Kudsk JE, Berti S, De Backer O, Aguirre D, Fassini G, Cruz-Gonzalez I, Grassi G, Tondo C. Use of intracardiac compared with transesophageal echocardiography for left atrial appendage occlusion in the Amulet observational Study. JACC Cardiovasc Interv. 2019;12(11):1030–9. https://doi.org/10.1016/j.jcin.2019.04.035.

    Article  PubMed  Google Scholar 

  7. Korsholm K, Samaras A, Andersen A, Jensen JM, Nielsen-Kudsk JE. The Watchman FLX device: first European experience and feasibility of intracardiac echocardiography to guide implantation. JACC Clin Electrophysiol. 2020;6(13):1633–42. https://doi.org/10.1016/j.jacep.2020.06.028.

    Article  PubMed  Google Scholar 

  8. Akella K, Murtaza G, Turagam M, Sharma S, Madoukh B, Amin A, Gopinathannair R, Lakkireddy D. Evaluating the role of transesophageal echocardiography (TEE) or intracardiac echocardiography (ICE) in left atrial appendage occlusion: a meta-analysis. J Interv Card Electrophysiol. 2021;60(1):41–8. https://doi.org/10.1007/s10840-019-00677-x.

    Article  PubMed  Google Scholar 

  9. Gianni C, Horton RP, Della Rocca DG, Mohanty S, Al-Ahmad A, Bassiouny MA, Burkhardt JD, Gallinghouse GJ, Hranitzky PM, Sanchez JE, Natale A. Intracardiac echocardiography- versus transesophageal echocardiography-guided left atrial appendage occlusion with Watchman FLX. J Cardiovasc Electrophysiol. 2021;32(10):2781–4. https://doi.org/10.1111/jce.15220.

    Article  PubMed  Google Scholar 

  10. Galea R, De Marco F, Meneveau N, Aminian A, Anselme F, Gräni C, Huber AT, Teiger E, Iriart X, Babongo Bosombo F, Heg D, Franzone A, Vranckx P, Fischer U, Pedrazzini G, Bedogni F, Räber L, Valgimigli M. Amulet or Watchman Device for percutaneous left atrial appendage closure: primary results of the SWISS-APERO randomized clinical trial. Circulation. 2022;145(10):724–38. https://doi.org/10.1161/CIRCULATIONAHA.121.057859.

    Article  PubMed  Google Scholar 

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Correspondence to Kousik Krishnan.

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Kousik Krishnan, MD, consulting fees from Zoll. Moeen Saleem, MD, consulting fees from Medtronic and Boston Scientific and has received speaking fees from Janssen.

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Krishnan, K., Saleem, M. Left atrial appendage occlusion: does it get the seal of approval?. J Interv Card Electrophysiol 66, 253–254 (2023). https://doi.org/10.1007/s10840-022-01381-z

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  • DOI: https://doi.org/10.1007/s10840-022-01381-z

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