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NLRP3 inflammasome: a potential target for predicting arrhythmia recurrence after atrial fibrillation ablation

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References

  1. Liu Y, Luo D, Liu E, et al. MiRNA21 and IL-18 levels in left atrial blood in patients with atrial fibrillation undergoing cryoablation and their predictive value for recurrence of atrial fibrillation. J Interv Card Electrophysiol. 2022;64(1):111–20.

    Article  Google Scholar 

  2. Zhang WJ, Chen SJ, Zhou SC, Wu SZ, Wang H. Inflammasomes and fibrosis. Front Immunol. 2021;12:643149.

    Article  CAS  Google Scholar 

  3. Haneklaus M, O’Neill LA. NLRP3 at the interface of metabolism and inflammation. Immunol Rev. 2015;265(1):53–62.

    Article  CAS  Google Scholar 

  4. Butts B, Gary RA, Dunbar SB, Butler J. The importance of NLRP3 inflammasome in heart failure. J Card Fail. 2015;21(7):586–93.

    Article  CAS  Google Scholar 

  5. Takahashi M. Cell-Specific Roles of NLRP3 Inflammasome in myocardial infarction. J Cardiovasc Pharmacol. 2019;74(3):188–93.

    Article  CAS  Google Scholar 

  6. Yao C, Veleva T, Scott L Jr, et al. Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation. Circulation. 2018;138(20):2227–42.

    Article  CAS  Google Scholar 

  7. Heijman J, Muna AP, Veleva T, et al. Atrial myocyte NLRP3/CaMKII nexus forms a substrate for postoperative atrial fibrillation. Circ Res. 2020;127(8):1036–55.

    Article  CAS  Google Scholar 

  8. Silvis MJM, Fiolet ATL, Opstal TSJ, et al. Colchicine reduces extracellular vesicle NLRP3 inflammasome protein levels in chronic coronary disease: a LoDoCo2 biomarker substudy. Atherosclerosis. 2021;334:93–100.

    Article  CAS  Google Scholar 

  9. Varghese B, Feldman DI, Chew C, et al. (2021) Inflammation, atrial fibrillation, and the potential role for colchicine therapy. Heart Rhythm 02. 2021;2(3):298–303.

    Article  Google Scholar 

  10. Deftereos S, Giannopoulos G, Kossyvakis C, et al. Colchicine for prevention of early atrial fibrillation recurrence after pulmonary vein isolation: a randomized controlled study. J Am Coll Cardiol. 2012;60:1790–6.

    Article  CAS  Google Scholar 

  11. Sethwala AM, Goh I, Amerena JV. Combating inflammation in cardiovascular disease. Heart Lung Circ. 2021;30(2):197–206.

    Article  Google Scholar 

  12. Hu YF, Chen YJ, Lin YJ, Chen SA. Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol. 2015;12(4):230–43.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Cardiology, Liaocheng People’s Hospital, Affiliated to Shandong First Medical University, Liaocheng, 252000, People’s Republic of China

    Qian-Feng Han, Jia-Hui Liu & De-Gang Mo

  2. Department of Neurology, Mengyin County Hospital, Linyi, 276200, People’s Republic of China

    Zhen-Dong Zhu

Authors
  1. Qian-Feng Han
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  2. Jia-Hui Liu
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  3. Zhen-Dong Zhu
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  4. De-Gang Mo
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Correspondence to De-Gang Mo.

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This comment refers to the article available at https://doi.org/10.1007/s10840-022-01125-z.

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Han, QF., Liu, JH., Zhu, ZD. et al. NLRP3 inflammasome: a potential target for predicting arrhythmia recurrence after atrial fibrillation ablation. J Interv Card Electrophysiol 65, 589–590 (2022). https://doi.org/10.1007/s10840-022-01334-6

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  • DOI: https://doi.org/10.1007/s10840-022-01334-6

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